Primary care guidelines provide a reference point to guide clinicians based on a systematic
review of the literature, contextualised by expert clinical opinion. These guidelines develop a …

Objective To perform a literature review of the thermal and mechanical antinociceptive
devices used in pharmacological studies in standing horses published after 2011 (2012 …

Background Standing surgery avoids the risks of general anaesthesia in horses. Objectives
To assess sedation, antinociception and gastrointestinal motility in standing horses after a …

Objective To evaluate intravenous (IV) detomidine with methadone in horses to identify a
combination which provides sedation and antinociception without adverse effects. Study …

The aim of this study was to compare the effects of methadone combined with detomidine or
acepromazine on the quality of sedation and its influence over dissociative anesthesia in …

Background Continuous-rate infusion (CRI) of drugs results in more stable plasma drug
concentrations than administration of intermittent boluses, thus providing greater stability of …

Reasons for performing study To investigate two protocols to provide antinociception in
horses. Objectives To evaluate the antinociceptive effects of intravenous methadone …

Individual variation in opioid sensitivity can have a profound impact on the safety and
efficacy of equine veterinary treatments, with the ability to adequately manage equine pain …

The lack of standardization of sedation scales in horses limits the reproducibility between
different studies. This prospective, randomized, blinded, horizontal and controlled trial aimed …

Reasons for performing study To validate a model for investigating the effects of analgesic
drugs on mechanical, thermal and electrical stimulation testing. Objectives To investigate …