A call for systematic research on solute carriers
A Cesar-Razquin, B Snijder, T Frappier-Brinton… - Cell, 2015 - cell.com
Solute carrier (SLC) membrane transport proteins control essential physiological functions,
including nutrient uptake, ion transport, and waste removal. SLCs interact with several …
including nutrient uptake, ion transport, and waste removal. SLCs interact with several …
Information retrieval and text mining technologies for chemistry
Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …
reports, or the web is a pressing need shared by researchers and patent attorneys from …
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
SD Harding, JL Sharman, E Faccenda… - Nucleic acids …, 2018 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, www.
guidetopharmacology. org) and its precursor IUPHAR-DB, have captured expert-curated …
guidetopharmacology. org) and its precursor IUPHAR-DB, have captured expert-curated …
The ChEMBL database in 2017
ChEMBL is an open large-scale bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since …
previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since …
An open source chemical structure curation pipeline using RDKit
Abstract Background The ChEMBL database is one of a number of public databases that
contain bioactivity data on small molecule compounds curated from diverse sources …
contain bioactivity data on small molecule compounds curated from diverse sources …
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
C Southan, JL Sharman, HE Benson… - Nucleic acids …, 2016 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, http://www.
guidetopharmacology. org) provides expert-curated molecular interactions between …
guidetopharmacology. org) provides expert-curated molecular interactions between …
The ChEMBL bioactivity database: an update
ChEMBL is an open large-scale bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012 Nucleic Acids Research Database Issue. Since then, a …
previously described in the 2012 Nucleic Acids Research Database Issue. Since then, a …
WikiPathways: capturing the full diversity of pathway knowledge
Abstract WikiPathways (http://www. wikipathways. org) is an open, collaborative platform for
capturing and disseminating models of biological pathways for data visualization and …
capturing and disseminating models of biological pathways for data visualization and …
The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
AJ Pawson, JL Sharman, HE Benson… - Nucleic acids …, 2014 - academic.oup.com
Abstract The International Union of Basic and Clinical Pharmacology/British
Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www …
Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY (http://www …
Shifting from the single to the multitarget paradigm in drug discovery
JL Medina-Franco, MA Giulianotti, GS Welmaker… - Drug discovery today, 2013 - Elsevier
Increasing evidence that several drug compounds exert their effects through interactions
with multiple targets is boosting the development of research fields that challenge the data …
with multiple targets is boosting the development of research fields that challenge the data …