Beyond hemostasis: platelet innate immune interactions and thromboinflammation
J Mandel, M Casari, M Stepanyan, A Martyanov… - International journal of …, 2022 - mdpi.com
There is accumulating evidence that platelets play roles beyond their traditional functions in
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …
The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases
L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
ED Hottz, IG Azevedo-Quintanilha… - Blood, The Journal …, 2020 - ashpublications.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …
Innate immune receptors in platelets and platelet-leukocyte interactions
PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …
inflammatory effector cells that can influence both innate and adaptive immune responses …
Platelets and infection–an emerging role of platelets in viral infection
A Assinger - Frontiers in immunology, 2014 - frontiersin.org
Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis.
While platelet activation and elevated platelet counts (thrombocytosis) are associated with …
While platelet activation and elevated platelet counts (thrombocytosis) are associated with …
Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2
Platelet-leukocyte interactions amplify inflammatory reactions, but the underlying
mechanism is still unclear. CLEC5A and CLEC2 are spleen tyrosine kinase (Syk)-coupled C …
mechanism is still unclear. CLEC5A and CLEC2 are spleen tyrosine kinase (Syk)-coupled C …
Thrombocytopenia in virus infections
M Raadsen, J Du Toit, T Langerak… - Journal of clinical …, 2021 - mdpi.com
Thrombocytopenia, which signifies a low platelet count usually below 150× 109/L, is a
common finding following or during many viral infections. In clinical medicine, mild …
common finding following or during many viral infections. In clinical medicine, mild …
Platelets in immune response to virus and immunopathology of viral infections
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation,
platelets are now recognized as major inflammatory cells with key roles in the innate and …
platelets are now recognized as major inflammatory cells with key roles in the innate and …
Role of platelets in detection and regulation of infection
I Portier, RA Campbell - Arteriosclerosis, thrombosis, and vascular …, 2021 - Am Heart Assoc
Platelets are classically known as essential mediators of hemostasis and thrombosis.
However, in recent years, platelets have gained recognition for their inflammatory functions …
However, in recent years, platelets have gained recognition for their inflammatory functions …
Thrombocytopenia in dengue: interrelationship between virus and the imbalance between coagulation and fibrinolysis and inflammatory mediators
EL Azeredo, RQ Monteiro… - Mediators of …, 2015 - Wiley Online Library
Dengue is an infectious disease caused by dengue virus (DENV). In general, dengue is a
self‐limiting acute febrile illness followed by a phase of critical defervescence, in which …
self‐limiting acute febrile illness followed by a phase of critical defervescence, in which …