Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

The term cirrhosis-associated immune dysfunction (CAID) comprises the distinctive
spectrum of immune alterations associated with the course of end-stage liver disease …

Tumour necrosis factor-α (TNF) is a multifunctional cytokine. First recognized as an
endogenous soluble factor that induces necrosis of solid tumours, TNF became increasingly …

Alcoholic liver disease (ALD) is a complex process that includes a wide spectrum of hepatic
lesions, from steatosis to cirrhosis. Cell injury, inflammation, oxidative stress, regeneration …

Hepatic lipid metabolism is a series of complex processes that control influx and efflux of not
only hepatic lipid pools, but also organismal pools. Lipid homeostasis is usually tightly …

Alcohol consumption is a predominant etiological factor in the pathogenesis of chronic liver
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …

Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …

Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious
health problems worldwide. These two diseases have similar pathological spectra, ranging …

Alcoholic and nonalcoholic fatty liver disease (ALD and NAFLD) are the predominant
causes of liver-related mortality in Western countries. We have shown that limiting classical …

The NLRP3 inflammasome, a caspase‐1 activation platform, plays a key role in the
modulation of liver inflammation and fibrosis. Here, we tested the hypothesis that interleukin …