Gated transformations from egocentric to allocentric reference frames involving retrosplenial cortex, entorhinal cortex, and hippocampus
This paper reviews the recent experimental finding that neurons in behaving rodents show
egocentric coding of the environment in a number of structures associated with the …
egocentric coding of the environment in a number of structures associated with the …
The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease
Y Tang, Y Yan, J Mao, J Ni, H Qing - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …
Precisely timed theta oscillations are selectively required during the encoding phase of memory
Brain oscillations have been hypothesized to support cognitive function by coordinating
spike timing within and across brain regions, yet it is often not known when timing is either …
spike timing within and across brain regions, yet it is often not known when timing is either …
Spatial memory requires hypocretins to elevate medial entorhinal gamma oscillations
Y Liao, R Wen, S Fu, X Cheng, S Ren, M Lu, L Qian… - Neuron, 2024 - cell.com
The hypocretin (Hcrt)(also known as orexin) neuropeptidic wakefulness-promoting system is
implicated in the regulation of spatial memory, but its specific role and mechanisms remain …
implicated in the regulation of spatial memory, but its specific role and mechanisms remain …
Optogenetic frequency scrambling of hippocampal theta oscillations dissociates working memory retrieval from hippocampal spatiotemporal codes
The precise temporal coordination of activity in the brain is thought to be fundamental for
memory function. Inhibitory neurons in the medial septum provide a prominent source of …
memory function. Inhibitory neurons in the medial septum provide a prominent source of …
Neuromodulator-dependent synaptic tagging and capture retroactively controls neural coding in spiking neural networks
AB Lehr, J Luboeinski, C Tetzlaff - Scientific Reports, 2022 - nature.com
Events that are important to an individual's life trigger neuromodulator release in brain areas
responsible for cognitive and behavioral function. While it is well known that the presence of …
responsible for cognitive and behavioral function. While it is well known that the presence of …
Septo-hippocampal dynamics and the encoding of space and time
Encoding an event in memory requires neural activity to represent multiple dimensions of
behavioral experience in space and time. Recent experiments have explored the influence …
behavioral experience in space and time. Recent experiments have explored the influence …
Angular and linear speed cells in the parahippocampal circuits
An essential role of the hippocampal region is to integrate information to compute and
update representations. How this transpires is highly debated. Many theories hinge on the …
update representations. How this transpires is highly debated. Many theories hinge on the …
Ketamine evoked disruption of entorhinal and hippocampal spatial maps
Ketamine, a rapid-acting anesthetic and acute antidepressant, carries undesirable spatial
cognition side effects including out-of-body experiences and spatial memory impairments …
cognition side effects including out-of-body experiences and spatial memory impairments …
Coherently remapping toroidal cells but not grid cells are responsible for path integration in virtual agents
It is widely believed that grid cells provide cues for path integration, with place cells
encoding an animal's location and environmental identity. When entering a new …
encoding an animal's location and environmental identity. When entering a new …