Adhesion mechanisms in platelet function

ZM Ruggeri, GL Mendolicchio - Circulation research, 2007 - Am Heart Assoc
Platelet adhesion is an essential function in response to vascular injury and is generally
viewed as the first step during which single platelets bind through specific membrane …

Platelet adhesion under flow

ZM Ruggeri - Microcirculation, 2009 - Taylor & Francis
Platelet-adhesive mechanisms play a well-defined role in hemostasis and thrombosis, but
evidence continues to emerge for a relevant contribution to other pathophysiological …

Glial cell influence on the human blood‐brain barrier

A Prat, K Biernacki, K Wosik, JP Antel - Glia, 2001 - Wiley Online Library
The blood‐brain barrier (BBB) is a specialized structure of the central nervous system (CNS)
that restricts immune cell migration and soluble molecule diffusion from the systemic …

Pulmonary arterial hypertension: a comparison between children and adults

RJ Barst, SI Ertel, M Beghetti… - European Respiratory …, 2011 - Eur Respiratory Soc
The characteristics of pulmonary arterial hypertension (PAH), including pathology,
symptoms, diagnosis and treatment are reviewed in children and adults. The histopathology …

von Willebrand factor and von Willebrand disease [published erratum appears in Blood 1988 Mar; 71 (3): 830]

ZM Ruggeri, TS Zimmerman - 1987 - ashpublications.org
Progress has occurred in the past several years in the understanding of the structure and
function of von Willebrand factor (vWF). This multimeric glycoprotein exhibits a dual role, that …

VEGF gene delivery to muscle: potential role for vasculogenesis in adults

ML Springer, AS Chen, PE Kraft, M Bednarski, HM Blau - Molecular cell, 1998 - cell.com
Constitutive expression of VEGF after implantation of genetically engineered myoblasts into
non-ischemic muscle led to an increase in vascular structures. Previously, effects of VEGF …

Preliminary post-mortem COVID-19 evidence of endothelial injury and factor VIII hyperexpression

L Cipolloni, F Sessa, G Bertozzi, B Baldari, S Cantatore… - Diagnostics, 2020 - mdpi.com
(1) Background: The current outbreak of COVID-19 infection is an ongoing challenge and a
major threat to public health that requires surveillance, prompt diagnosis, as well as …

Physiology of fibronectin.

DF Mosher - Annual review of medicine, 1984 - europepmc.org
Fibronectin is a major protein of blood and tissues. It has been intensively studied because
of its many interactions with cells and other macromolecules. Fibronectin is a principal …

Synthesis and secretion of thrombospondin by cultured human endothelial cells.

DF Mosher, MJ Doyle, EA Jaffe - The Journal of cell biology, 1982 - rupress.org
Thrombospondin, the major glycoprotein released from alpha-granules of thrombin-
stimulated platelets, is a disulfide-bonded trimer of 160 kilodalton subunits and apparently …

Platelet activation by extracellular matrix proteins in haemostasis and thrombosis

SP Watson - Current pharmaceutical design, 2009 - ingentaconnect.com
The prevention of excessive blood loss to avoid fatal haemorrhage is a pivotal process for all
organisms possessing a circulatory system. Increased circulating blood volume and …