During almost 40 years of use, the micronucleus assay (MN) has become one of the most
popular methods to assess genotoxicity of different chemical and physical factors, including …

The present review describes available evidence about the fate of micronuclei and
micronucleated cells. Micronuclei are small, extranuclear chromatin bodies surrounded by a …

Micronuclei (MN), the small nucleus-like bodies separated from the primary nucleus, can
exist in cells with numerical and/or structural chromosomal aberrations in apparently normal …

Simple Summary Chromosome instability (CIN) is characterized by an increased
accumulation of numerical and structural changes in chromosomes and is a common feature …

Micronucleus (MN) is the small nucleus that forms whenever a chromosome or its fragment
is not incorporated into one of the daughter nuclei during cell division. Any form of genotoxic …

Micronuclei, whole or fragmented chromosomes spatially separated from the main nucleus,
are associated with genomic instability and have been identified as drivers of tumorigenesis …

The lymphocyte cytokinesis-block micronucleus (CBMN) assay has been applied in
hundreds of in vivo biomonitoring studies of humans exposed to genotoxic chemicals …

Micronuclei (MNi) are extranuclear DNA-containing structures that form upon mitotic exit
from unsegregated chromosome fragments or anaphase lagging (whole) chromosomes …

Cellular responses to stimuli can evolve over time, resulting in distinct early and late phases
in response to a single signal. DNA damage induces a complex response that is largely …

Cells are constantly confronted with endogenous and exogenous factors that affect their
genomes. Eons of evolution have allowed the cellular mechanisms responsible for …