Polymeric amorphous solid dispersions: a review of amorphization, crystallization, stabilization, solid-state characterization, and aqueous solubilization of …
S Baghel, H Cathcart, NJ O'Reilly - Journal of pharmaceutical sciences, 2016 - Elsevier
Poor water solubility of many drugs has emerged as one of the major challenges in the
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …
pharmaceutical world. Polymer-based amorphous solid dispersions have been considered …
[HTML][HTML] The future of pharmaceutical manufacturing sciences
J Rantanen, J Khinast - Journal of pharmaceutical sciences, 2015 - Elsevier
The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …
solutions and fundamental scientific work, enabling the production of highly engineered …
[HTML][HTML] Polymers in pharmaceutical additive manufacturing: A balancing act between printability and product performance
Materials and manufacturing processes share a common purpose of enabling the
pharmaceutical product to perform as intended. This review on the role of polymeric …
pharmaceutical product to perform as intended. This review on the role of polymeric …
Glass-transition temperature of the β-relaxation as the major predictive parameter for recrystallization of neat amorphous drugs
Recrystallization of amorphous drugs is currently limiting the simple approach to improve
solubility and bioavailability of poorly water-soluble drugs by amorphization of a crystalline …
solubility and bioavailability of poorly water-soluble drugs by amorphization of a crystalline …
Physical stability of amorphous solid dispersions: a physicochemical perspective with thermodynamic, kinetic and environmental aspects
X Lin, Y Hu, L Liu, L Su, N Li, J Yu, B Tang… - Pharmaceutical …, 2018 - Springer
Abstract Purpose Amorphous solid dispersions (ASDs) have been widely used in the
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …
Linking Glass‐Transition Behavior to Photophysical and Charge Transport Properties of High‐Mobility Conjugated Polymers
M Xiao, A Sadhanala, M Abdi‐Jalebi… - Advanced Functional …, 2021 - Wiley Online Library
The measurement of the mechanical properties of conjugated polymers can reveal highly
relevant information linking optoelectronic properties to underlying microstructures and the …
relevant information linking optoelectronic properties to underlying microstructures and the …
[HTML][HTML] Role of crystal disorder and mechanoactivation in solid-state stability of pharmaceuticals
Common energy-intensive processes applied in oral solid dosage development, such as
milling, sieving, blending, compaction, etc. generate particles with surface and bulk crystal …
milling, sieving, blending, compaction, etc. generate particles with surface and bulk crystal …
[HTML][HTML] Dynamic mechanical and thermal properties of clear aligners after thermoforming and aging
K Dalaie, SM Fatemi, S Ghaffari - Progress in Orthodontics, 2021 - Springer
Background Based on the role of properties of aligner materials on their efficiency, we aimed
to assess their thermomechanical properties after thermoforming and simulated aging …
to assess their thermomechanical properties after thermoforming and simulated aging …
Complementarity of mDSC, DMA, and DRS Techniques in the Study of Tg and Sub-Tg Transitions in Amorphous Solids: PVPVA, Indomethacin, and Amorphous …
S Thayumanasundaram, TR Venkatesan… - Molecular …, 2022 - ACS Publications
Recently, glasses, a subset of amorphous solids, have gained attention in various fields,
such as polymer chemistry, optical fibers, and pharmaceuticals. One of their characteristic …
such as polymer chemistry, optical fibers, and pharmaceuticals. One of their characteristic …
Dehydration characteristics and evolution of physicochemical properties of Platycodon grandiflorum (Jacq. A. DC.) roots (PGR) during pulse-spouted microwave …
Abstract Platycodon grandiflorum (Jacq. A. DC.) root (PGR) is a famous edible and
medicinal herb which contains lots of bioactive components that were beneficial for people …
medicinal herb which contains lots of bioactive components that were beneficial for people …