Cycloadditions and cyclizations of acetylenic, allenic, and conjugated dienyl sulfones
TG Back, KN Clary, D Gao - Chemical reviews, 2010 - ACS Publications
Sulfones display a diverse range of behavior and possess unique features that make them
valuable for numerous types of synthetic applications. As a result of their utility and …
valuable for numerous types of synthetic applications. As a result of their utility and …
Recent Advances on the Synthesis and Application of Tetrahydro‐β‐Carbolines
Tetrahydro‐β‐carbolines (THβCs) also known as tryptolines serve as important structural
elements in natural products and pharmaceutical compounds, and they are also utilized in …
elements in natural products and pharmaceutical compounds, and they are also utilized in …
[HTML][HTML] In-vitro and in-silico studies of annelated 1, 4, 7, 8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase
Based on previous finding showing 2, 3, 6, 11-tetrahydro-1H-azocino [4, 5-b] indole as
suitable scaffold of novel inhibitors of acetylcholinesterase (AChE), a main target of drugs for …
suitable scaffold of novel inhibitors of acetylcholinesterase (AChE), a main target of drugs for …
Synthesis of Novel Benzo[b][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors
LN Kulikova, GR Raesi, DD Levickaya, R Purgatorio… - Molecules, 2023 - mdpi.com
In this work, 2-alkyl-10-chloro-1, 2, 3, 4-tetrahydrobenzo [b][1, 6] naphthyridines were
obtained and their reactivity was studied. Novel derivatives of the tricyclic scaffold, including …
obtained and their reactivity was studied. Novel derivatives of the tricyclic scaffold, including …
One-pot synthesis of 6, 11-dihydro-5 H-indolizino [8, 7-b] indoles via sequential formation of β-enamino ester, Michael addition and Pictet–Spengler reactions
D Zhu, J Sun, CG Yan - RSC Advances, 2014 - pubs.rsc.org
β-Enamino esters generated from addition of tryptamines to alkyl propiolates reacted with 3-
phenacylideneoxindoles in the presence of anhydrous ZnCl2 to give functionalized 2 …
phenacylideneoxindoles in the presence of anhydrous ZnCl2 to give functionalized 2 …
Benzo [1, 4] diazocinone/Pyrrole Ensembles via the Catalyst‐Free Insertion of Pyrrolylacetylenic Ketones into Benzimidazoles
KV Belyaeva, LP Nikitina, VS Gen', IV Saliy… - …, 2022 - Wiley Online Library
Early unknown pharmaceutically oriented heterocyclic systems of benzo [1, 4]
diazocinone/pyrrole ensembles have been synthesized in up to 93% yields by the catalyst …
diazocinone/pyrrole ensembles have been synthesized in up to 93% yields by the catalyst …
Three-Component Reaction for the Convenient Synthesis of Functionalized 3-{1-[2-(1H-Indol-3-yl) ethyl]-4, 5, 6, 7-tetrahydro-1H-indol-3-yl} indolin-2-ones
YH Jiang, CG Yan - Synthesis, 2016 - thieme-connect.com
A simple synthetic protocol was developed for the efficient synthesis of functionalized 3-{1-[2-
(1H-indol-3-yl) ethyl]-4, 5, 6, 7-tetrahydro-1H-indol-3-yl} indolin-2-ones in high yield via three …
(1H-indol-3-yl) ethyl]-4, 5, 6, 7-tetrahydro-1H-indol-3-yl} indolin-2-ones in high yield via three …
Part I: Diastereoselective Reactions Involving β‐Mono‐and β, β′‐Disubstituted Alkylidene Oxindoles: Pondering Alkene Geometry
Diastereoselective reactions supported by metals and nonmetals offer a multifaceted path
for the synthesis of robust intermediates of value to academia and industry. The reactions …
for the synthesis of robust intermediates of value to academia and industry. The reactions …
Synthesis of 6-aryl-Substituted Azocino-[5,4-b]indoles from 1-aryl-Substituted 2-Ethyltetrahydro-β-Carbolines
LG Voskressensky, TN Borisova… - Chemistry of …, 2014 - Springer
We optimized the reaction of tetrahydropyridine ring expansion in 1-aryl-substituted
tetrahydro-β-carbolines by the action of activated alkynes and achieved higher than 70 …
tetrahydro-β-carbolines by the action of activated alkynes and achieved higher than 70 …
The first synthesis of 6-(phenylethynyl)-substituted tetrahydroazocino[5,4-b]indoles
LG Voskressensky, AA Titov, MS Kobzev… - Chemistry of …, 2016 - Springer
The first synthesis of 6-(phenylethynyl)-substituted tetrahydroazocino[5,4-b]indoles | SpringerLink
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