Cycloadditions and cyclizations of acetylenic, allenic, and conjugated dienyl sulfones

TG Back, KN Clary, D Gao - Chemical reviews, 2010 - ACS Publications
Sulfones display a diverse range of behavior and possess unique features that make them
valuable for numerous types of synthetic applications. As a result of their utility and …

Recent Advances on the Synthesis and Application of Tetrahydro‐β‐Carbolines

Y Du, A Semghouli, H Mei, L Kiss… - Advanced Synthesis & …, 2024 - Wiley Online Library
Tetrahydro‐β‐carbolines (THβCs) also known as tryptolines serve as important structural
elements in natural products and pharmaceutical compounds, and they are also utilized in …

[HTML][HTML] In-vitro and in-silico studies of annelated 1, 4, 7, 8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase

M de Candia, AA Titov, A Viayna, LN Kulikova… - Chemico-Biological …, 2023 - Elsevier
Based on previous finding showing 2, 3, 6, 11-tetrahydro-1H-azocino [4, 5-b] indole as
suitable scaffold of novel inhibitors of acetylcholinesterase (AChE), a main target of drugs for …

Synthesis of Novel Benzo[b][1,6]naphthyridine Derivatives and Investigation of Their Potential as Scaffolds of MAO Inhibitors

LN Kulikova, GR Raesi, DD Levickaya, R Purgatorio… - Molecules, 2023 - mdpi.com
In this work, 2-alkyl-10-chloro-1, 2, 3, 4-tetrahydrobenzo [b][1, 6] naphthyridines were
obtained and their reactivity was studied. Novel derivatives of the tricyclic scaffold, including …

One-pot synthesis of 6, 11-dihydro-5 H-indolizino [8, 7-b] indoles via sequential formation of β-enamino ester, Michael addition and Pictet–Spengler reactions

D Zhu, J Sun, CG Yan - RSC Advances, 2014 - pubs.rsc.org
β-Enamino esters generated from addition of tryptamines to alkyl propiolates reacted with 3-
phenacylideneoxindoles in the presence of anhydrous ZnCl2 to give functionalized 2 …

Benzo [1, 4] diazocinone/Pyrrole Ensembles via the Catalyst‐Free Insertion of Pyrrolylacetylenic Ketones into Benzimidazoles

KV Belyaeva, LP Nikitina, VS Gen', IV Saliy… - …, 2022 - Wiley Online Library
Early unknown pharmaceutically oriented heterocyclic systems of benzo [1, 4]
diazocinone/pyrrole ensembles have been synthesized in up to 93% yields by the catalyst …

Three-Component Reaction for the Convenient Synthesis of Functionalized 3-{1-[2-(1H-Indol-3-yl) ethyl]-4, 5, 6, 7-tetrahydro-1H-indol-3-yl} indolin-2-ones

YH Jiang, CG Yan - Synthesis, 2016 - thieme-connect.com
A simple synthetic protocol was developed for the efficient synthesis of functionalized 3-{1-[2-
(1H-indol-3-yl) ethyl]-4, 5, 6, 7-tetrahydro-1H-indol-3-yl} indolin-2-ones in high yield via three …

Part I: Diastereoselective Reactions Involving β‐Mono‐and β, β′‐Disubstituted Alkylidene Oxindoles: Pondering Alkene Geometry

M Ganesh, MP Rao, SJ Mirajakar - Asian Journal of Organic …, 2018 - Wiley Online Library
Diastereoselective reactions supported by metals and nonmetals offer a multifaceted path
for the synthesis of robust intermediates of value to academia and industry. The reactions …

Synthesis of 6-aryl-Substituted Azocino-[5,4-b]indoles from 1-aryl-Substituted 2-Ethyltetrahydro-β-Carbolines

LG Voskressensky, TN Borisova… - Chemistry of …, 2014 - Springer
We optimized the reaction of tetrahydropyridine ring expansion in 1-aryl-substituted
tetrahydro-β-carbolines by the action of activated alkynes and achieved higher than 70 …

The first synthesis of 6-(phenylethynyl)-substituted tetrahydroazocino[5,4-b]indoles

LG Voskressensky, AA Titov, MS Kobzev… - Chemistry of …, 2016 - Springer
The first synthesis of 6-(phenylethynyl)-substituted tetrahydroazocino[5,4-b]indoles | SpringerLink
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