[HTML][HTML] The silent threat to women's fertility: uncovering the devastating effects of oxidative stress
A Kaltsas, A Zikopoulos, E Moustakli, A Zachariou… - Antioxidants, 2023 - mdpi.com
Oxidative stress (OS), which arises through an imbalance between the formation of reactive
oxygen species (ROS) and antioxidant defenses, plays a key role in the pathophysiology of …
oxygen species (ROS) and antioxidant defenses, plays a key role in the pathophysiology of …
[HTML][HTML] Role of microRNAs in trophoblast invasion and spiral artery remodeling: implications for preeclampsia
H Hayder, Y Shan, Y Chen, JA O'Brien… - Frontiers in Cell and …, 2022 - frontiersin.org
It is now well-established that microRNAs (miRNAs) are important regulators of gene
expression. The role of miRNAs in placental development and trophoblast function is …
expression. The role of miRNAs in placental development and trophoblast function is …
[HTML][HTML] Prioritization of potential causative genes for schizophrenia in placenta
Our earlier work has shown that genomic risk for schizophrenia converges with early life
complications in affecting risk for the disorder and sex-biased neurodevelopmental …
complications in affecting risk for the disorder and sex-biased neurodevelopmental …
New immune horizons in therapeutics and diagnostic approaches to Preeclampsia
Hypertensive disorders of pregnancy (HDP) are one of the commonest maladies, affecting
5%–10% of pregnancies worldwide. The American College of Obstetricians and …
5%–10% of pregnancies worldwide. The American College of Obstetricians and …
Cytoprotective and genoprotective effects of taxifolin against oxidative damage in HTR-8/SVneo human trophoblast cells
M Bruić, A Pirković, A Vilotić… - …, 2023 - academic.oup.com
An increase of reactive oxygen species in the placenta and oxidative disbalance has been
recognized as a significant factor contributing to pregnancy complications. Dietary intake of …
recognized as a significant factor contributing to pregnancy complications. Dietary intake of …
Modeling the Progression of Placental Transport from Early‐to Late‐Stage Pregnancy by Tuning Trophoblast Differentiation and Vascularization
S Kouthouridis, A Sotra, Z Khan… - Advanced …, 2023 - Wiley Online Library
The early‐stage placental barrier is characterized by a lack of fetal circulation and by a thick
trophoblastic barrier, whereas the later‐stage placenta consists of vascularized chorionic …
trophoblastic barrier, whereas the later‐stage placenta consists of vascularized chorionic …
[HTML][HTML] Crosstalk between microRNA and oxidative stress in heart failure: A systematic review
D Klimczak-Tomaniak, J Haponiuk-Skwarlińska… - International Journal of …, 2022 - mdpi.com
Heart failure is defined as a clinical syndrome consisting of key symptoms and is due to a
structural and/or functional alteration of the heart that results in increased intracardiac …
structural and/or functional alteration of the heart that results in increased intracardiac …
[HTML][HTML] Oleuropein attenuates oxidative stress in human trophoblast cells
A Pirković, A Vilotić, S Borozan, M Nacka-Aleksić… - Antioxidants, 2023 - mdpi.com
Olive-derived bioactive compound oleuropein was evaluated against damage induced by
hydrogen peroxide in human trophoblast cells in vitro, by examining the changes in several …
hydrogen peroxide in human trophoblast cells in vitro, by examining the changes in several …
[HTML][HTML] Reduction in CgA-Derived CST Protein Level in HTR-8/SVneo and BeWo Trophoblastic Cell Lines Caused by the Preeclamptic Environment
M Bralewska, T Pietrucha, A Sakowicz - International Journal of …, 2023 - mdpi.com
One of the most dangerous complications of pregnancy is preeclampsia (PE), a disease
associated with a high risk of maternal and fetal mortality and morbidity. Although its etiology …
associated with a high risk of maternal and fetal mortality and morbidity. Although its etiology …
[HTML][HTML] Monosodium glutamate perturbs human trophoblast invasion and differentiation through a reactive oxygen species-mediated pathway: An in-vitro assessment
The overproduction of reactive oxygen species (ROS) has been associated with various
human diseases. ROS exert a multitude of biological effects with both physiological and …
human diseases. ROS exert a multitude of biological effects with both physiological and …