Kaempferol: antimicrobial properties, sources, clinical, and traditional applications
A Periferakis, K Periferakis, IA Badarau… - International journal of …, 2022 - mdpi.com
Flavonoids are a category of plant-derived compounds which exhibit a large number of
health-related effects. One of the most well-known and studied flavonoids is kaempferol …
health-related effects. One of the most well-known and studied flavonoids is kaempferol …
Kaempferol induces programmed cell death in Naegleria fowleri
HG Lê, JM Kang, TC Võ, BK Na - Phytomedicine, 2023 - Elsevier
Background Naegleria fowleri is a brain-eating amoeba causing a fatal brain infection called
primary amoebic meningoencephalitis (PAM). Despite its high mortality over 95%, effective …
primary amoebic meningoencephalitis (PAM). Despite its high mortality over 95%, effective …
Application of Raman spectroscopy for characterization of the functional polarization of macrophages into M1 and M2 cells
ARB Ribeiro, ECO Silva, PMC Araújo, ST Souza… - … Acta Part A: Molecular …, 2022 - Elsevier
Macrophages are key cells in the immune inflammatory response that can be differentiated
into M1 and M2 phenotypes. Polarization has a critical therapeutic value, especially in …
into M1 and M2 phenotypes. Polarization has a critical therapeutic value, especially in …
Structural design, synthesis and antioxidant, antileishmania, anti-inflammatory and anticancer activities of a novel quercetin acetylated derivative
SVS da Silva, OM Barboza, JT Souza, ÉN Soares… - Molecules, 2021 - mdpi.com
Quercetin (Q) is a bioflavonoid with biological potential; however, poor solubility in water,
extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological …
extensive enzymatic metabolism and a reduced bioavailability limit its biopharmacological …
Solidagenone acts on promastigotes of L. amazonensis by inducing apoptosis-like processes on intracellular amastigotes by IL-12p70/ROS/NO pathway activation
BT da Silva Bortoleti, MD Gonçalves… - Phytomedicine, 2021 - Elsevier
Background Leishmaniasis is a neglected tropical disease caused by protozoan parasites of
the Leishmania genus. Currently, the treatment has limited effectiveness and high toxicity, is …
the Leishmania genus. Currently, the treatment has limited effectiveness and high toxicity, is …
[HTML][HTML] Flavonoid Aglycones in Species of Solanum
Solanum L. is the largest genus of the Solanaceae family, with approximately 1400 species,
which are distributed throughout the world. The genus has economic importance, including …
which are distributed throughout the world. The genus has economic importance, including …
3D‐Printed Acoustofluidic Devices for Raman Spectroscopy of Cells
Acoustofluidics technology can be used to trap live cells (and also micro/nanoparticles) in
microenvironments suitable for cell assays. Herein, a cheap and easy‐to‐fabricate device is …
microenvironments suitable for cell assays. Herein, a cheap and easy‐to‐fabricate device is …
Euterpe oleracea fruit (Açai)-enriched diet suppresses the development of experimental cerebral malaria induced by Plasmodium berghei (ANKA) infection
KRHM Oliveira, MLM Torres, N Kauffmann… - … Medicine and Therapies, 2022 - Springer
Background Cerebral malaria is one of the most severe complications attributed to protozoal
infection by Plasmodium falciparum, gaining prominence in children mortality rates in …
infection by Plasmodium falciparum, gaining prominence in children mortality rates in …
An anti‐leishmanial compound 4′,7‐dihydroxyflavone elicits ROS‐mediated apoptosis‐like death in Leishmania parasite
S Sasidharan, P Saudagar - The FEBS Journal, 2023 - Wiley Online Library
The treatment for leishmaniasis is currently plagued by side effects such as toxicity and the
emergence of drug resistance to the available repertoire of drugs, as well as the expense of …
emergence of drug resistance to the available repertoire of drugs, as well as the expense of …
Antileishmanial compounds from Connarus suberosus: Metabolomics, isolation and mechanism of action
LS Morais, RG Dusi, DP Demarque, RL Silva… - PLoS …, 2020 - journals.plos.org
Leishmaniasis is a disease impacting public health worldwide due to its high incidence,
morbidity and mortality. Available treatments are costly, lengthy and toxic, not to mention the …
morbidity and mortality. Available treatments are costly, lengthy and toxic, not to mention the …