International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine

RB Kreider, DS Kalman, J Antonio… - Journal of the …, 2017 - Taylor & Francis
Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have
consistently shown that creatine supplementation increases intramuscular creatine …

Creatine in health and disease

RB Kreider, JR Stout - Nutrients, 2021 - mdpi.com
Although creatine has been mostly studied as an ergogenic aid for exercise, training, and
sport, several health and potential therapeutic benefits have been reported. This is because …

Impact of predictive, preventive and precision medicine strategies in epilepsy

R Nabbout, M Kuchenbuch - Nature Reviews Neurology, 2020 - nature.com
Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

Creatine biosynthesis and transport in health and disease

MJC Curt, PM Voicu, M Fontaine, AF Dessein… - Biochimie, 2015 - Elsevier
Creatine is physiologically provided equally by diet and by endogenous synthesis from
arginine and glycine with successive involvements of arginine glycine amidinotransferase …

Chemistry of human breast milk—a comprehensive review of the composition and role of milk metabolites in child development

D Garwolinska, J Namiesnik, A Kot-Wasik… - Journal of agricultural …, 2018 - ACS Publications
Early nutrition has an enormous influence on a child's physiological function, immune
system maturation, and cognitive development. Human breast milk (HBM) is recognized as …

Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?

PJ Allen - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Athletes, body builders, and military personnel use dietary creatine as an ergogenic aid to
boost physical performance in sports involving short bursts of high-intensity muscle activity …

Creatine: endogenous metabolite, dietary, and therapeutic supplement

JT Brosnan, ME Brosnan - Annu. Rev. Nutr., 2007 - annualreviews.org
Creatine and phosphocreatine serve not only as an intracellular buffer for adenosine
triphosphate, but also as an energy shuttle for the movement of high-energy phosphates …

The biological basis of injury and neuroprotection in the fetal and neonatal brain

S Rees, R Harding, D Walker - International Journal of Developmental …, 2011 - Elsevier
A compromised intrauterine environment that delivers low levels of oxygen and/or nutrients,
or is infected or inflammatory, can result in fetal brain injury, abnormal brain development …

Synthesis and transport of creatine in the CNS: importance for cerebral functions

E Béard, O Braissant - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 297–313. Abstract Apart of its well known function of 'energetic
buffer'through the creatine/phosphocreatine/creatine kinase system allowing the …

Creatine deficiency syndromes and the importance of creatine synthesis in the brain

O Braissant, H Henry, E Béard, J Uldry - Amino acids, 2011 - Springer
Creatine deficiency syndromes, due to deficiencies in AGAT, GAMT (creatine synthesis
pathway) or SLC6A8 (creatine transporter), lead to complete absence or very strong …