Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm

J Bethony, S Brooker, M Albonico, SM Geiger… - The lancet, 2006 - thelancet.com
The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm,
are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in …

Protective immune mechanisms in helminth infection

RM Anthony, LI Rutitzky, JF Urban Jr… - Nature Reviews …, 2007 - nature.com
Important insights have recently been gained in our understanding of how host immune
responses mediate resistance to parasitic helminths and control associated pathological …

The genomic basis of parasitism in the Strongyloides clade of nematodes

VL Hunt, IJ Tsai, A Coghlan, AJ Reid, N Holroyd… - Nature …, 2016 - nature.com
Soil-transmitted nematodes, including the Strongyloides genus, cause one of the most
prevalent neglected tropical diseases. Here we compare the genomes of four Strongyloides …

“Rapid-impact interventions”: how a policy of integrated control for Africa's neglected tropical diseases could benefit the poor

DH Molyneux, PJ Hotez, A Fenwick - PLoS medicine, 2005 - journals.plos.org
“Rapid-Impact Interventions”: How a Policy of Integrated Control for Africa's Neglected
Tropical Diseases Could Benefit the Poor | PLOS Medicine Skip to main content …

The yin and yang of human soil-transmitted helminth infections

A Loukas, RM Maizels, PJ Hotez - International journal for parasitology, 2021 - Elsevier
The major soil-transmitted helminths that infect humans are the roundworms, whipworms
and hookworms. Soil-transmitted helminth infections rank among the most important …

Toxocariasis: America's most common neglected infection of poverty and a helminthiasis of global importance?

PJ Hotez, PP Wilkins - PLoS neglected tropical diseases, 2009 - journals.plos.org
Toxocariasis results from zoonotic transmission of the roundworms, Toxocara canis and T.
cati from dogs and cats, respectively. Infection occurs when humans accidentally ingest the …

Developing vaccines to combat hookworm infection and intestinal schistosomiasis

PJ Hotez, JM Bethony, DJ Diemert, M Pearson… - Nature Reviews …, 2010 - nature.com
Hookworm infection and schistosomiasis rank among the most important health problems in
developing countries. Both cause anaemia and malnutrition, and schistosomiasis also …

[HTML][HTML] Genome of the human hookworm Necator americanus

YT Tang, X Gao, BA Rosa, S Abubucker… - Nature …, 2014 - nature.com
The hookworm Necator americanus is the predominant soil-transmitted human parasite.
Adult worms feed on blood in the small intestine, causing iron-deficiency anemia …

Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths

DJ Diemert, AG Pinto, J Freire, A Jariwala… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Necator americanus Ancylostoma-secreted protein 2 (Na-ASP-2) is
secreted by infective hookworm larvae on entry into human hosts. Vaccination of laboratory …

Vaccines to combat the neglected tropical diseases

JM Bethony, RN Cole, X Guo, S Kamhawi… - Immunological …, 2011 - Wiley Online Library
The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious
diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm …