Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics
While functional MRI (fMRI) localizes brain activation and deactivation, functional MRS
(fMRS) provides insights into the underlying metabolic conditions. There is much interest in …
(fMRS) provides insights into the underlying metabolic conditions. There is much interest in …
Development of frontal GABA and glutamate supports excitation/inhibition balance from adolescence into adulthood
Animal and human postmortem studies provide evidence for changes in gamma-
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …
Spectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations
Spectral editing in in vivo 1H‐MRS provides an effective means to measure low‐
concentration metabolite signals that cannot be reliably measured by conventional MRS …
concentration metabolite signals that cannot be reliably measured by conventional MRS …
Multi-vendor standardized sequence for edited magnetic resonance spectroscopy
Spectral editing allows direct measurement of low-concentration metabolites, such as GABA,
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …
Effect of age on GABA+ and glutathione in a pediatric sample
BACKGROUND AND PURPOSE: Gamma-aminobutyric acid (GABA) is the primary inhibitory
neurotransmitter in the human brain and is implicated in several neuropathologies …
neurotransmitter in the human brain and is implicated in several neuropathologies …
[HTML][HTML] Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease
AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …
Advanced Hadamard-encoded editing of seven low-concentration brain metabolites: Principles of HERCULES
Purpose To demonstrate the framework of a novel Hadamard-encoded spectral editing
approach for simultaneously detecting multiple low-concentration brain metabolites in vivo …
approach for simultaneously detecting multiple low-concentration brain metabolites in vivo …
Precision of metabolite‐selective MRS measurements of glutamate, GABA and glutathione: A review of human brain studies
K Kanagasabai, L Palaniyappan… - NMR in …, 2024 - Wiley Online Library
Single‐voxel proton magnetic resonance spectroscopy (SV 1H‐MRS) is an in vivo
noninvasive imaging technique used to detect neurotransmitters and metabolites. It enables …
noninvasive imaging technique used to detect neurotransmitters and metabolites. It enables …
Glutamate measurements using edited MRS
Purpose To demonstrate J‐difference coediting of glutamate using Hadamard encoding and
reconstruction of Mescher‐Garwood‐edited spectroscopy (HERMES). Methods Density …
reconstruction of Mescher‐Garwood‐edited spectroscopy (HERMES). Methods Density …
Simultaneous edited MRS of GABA, glutathione, and ethanol
The aim of this work was to develop simultaneous edited MRS of γ‐aminobutyric acid
(GABA), glutathione (GSH), and ethanol (EtOH) using Hadamard encoding and …
(GABA), glutathione (GSH), and ethanol (EtOH) using Hadamard encoding and …