The 2‐Pyridyl Problem: Challenging Nucleophiles in Cross‐Coupling Arylations
XAF Cook, A de Gombert, J McKnight… - Angewandte …, 2021 - Wiley Online Library
Azine‐containing biaryls are ubiquitous scaffolds in many areas of chemistry, and efficient
methods for their synthesis are continually desired. Pyridine rings are prominent amongst …
methods for their synthesis are continually desired. Pyridine rings are prominent amongst …
Sustainable and practical formation of carbon–carbon and carbon–heteroatom bonds employing organo-alkali metal reagents
Metal-catalysed cross-coupling reactions are amongst the most widely used methods to
directly construct new bonds. In this connection, sustainable and practical protocols …
directly construct new bonds. In this connection, sustainable and practical protocols …
Continuous flow generation of highly reactive organometallic intermediates: a recent update
M Spennacchio, P Natho, M Andresini… - Journal of Flow …, 2024 - Springer
Reactive organometallic intermediates present a distinct opportunity for the creation of novel
carbon-carbon and carbon-heteroatom bonds. Whereas their utility in synthesis is well …
carbon-carbon and carbon-heteroatom bonds. Whereas their utility in synthesis is well …
Synthesis of pyridylsulfonium salts and their application in the formation of functionalized bipyridines
VK Duong, AM Horan, EM McGarrigle - Organic Letters, 2020 - ACS Publications
An S-selective arylation of pyridylsulfides with good functional group tolerance was
developed. To demonstrate synthetic utility, the resulting pyridylsulfonium salts were used in …
developed. To demonstrate synthetic utility, the resulting pyridylsulfonium salts were used in …
Flow chemistry of main group and transition metal complexes
T Scattolin, A Simoens, CV Stevens, SP Nolan - Trends in Chemistry, 2022 - cell.com
Continuous flow reactors have earned their place as an important technology in organic
synthesis, receiving increased interest in the past decade. The favorable heat and mass …
synthesis, receiving increased interest in the past decade. The favorable heat and mass …
Continuous flow as an enabling technology: a fast and versatile entry to functionalized glyoxal derivatives
F Lima, M Meisenbach, B Schenkel… - Organic & Biomolecular …, 2021 - pubs.rsc.org
We herein report two complementary strategies employing organolithium chemistry for the
synthesis of glyoxal derivatives. Micro-mixer technology allows for the generation of …
synthesis of glyoxal derivatives. Micro-mixer technology allows for the generation of …
Flow chemistry: A green opportunity for organochalcogen chemistry
The use of flow technologies is becoming popular among the chemists who are dealing with
organochalcogens compounds, especially those who usually work with organoselenium or …
organochalcogens compounds, especially those who usually work with organoselenium or …
Towards an approach to small-scale aryllithium flash flow chemistry using low-cost, low volume reactors
JAK Cochrane, AJ Rigby, RS Mulla - Journal of Flow Chemistry, 2024 - Springer
Two low-cost reactors for aryllithium generation and trapping with an electrophile in flow
have been developed for use with small quantities of limiting reagent (600 μ mol) using …
have been developed for use with small quantities of limiting reagent (600 μ mol) using …
Exploiting sulfinate coupling partners for the preparation of diversely functionalised heterocycles
J McKnight - 2022 - ora.ox.ac.uk
In the following thesis, sulfinates have been exploited for the formation of di (hetero)
arylmethanes and bi (hetero) aryls, either by being formed in situ or through a …
arylmethanes and bi (hetero) aryls, either by being formed in situ or through a …
Towards an approach to small-scale aryllithium flash flow chemistry using low-cost, low internal volume reactors.
J Cochrane, A Rigby, R Mulla - 2024 - chemrxiv.org
Two low-cost reactors for aryllithium generation and trapping with an electrophile in flow
chemistry have been developed for use with small quantities of limiting reagent (≤ 600 …
chemistry have been developed for use with small quantities of limiting reagent (≤ 600 …