Laboratory assays for Epstein-Barr virus-related disease

ML Gulley, W Tang - The Journal of molecular diagnostics, 2008 - Elsevier
Epstein-Barr virus (EBV) infects various cell types in a wide spectrum of benign and
malignant diseases. Laboratory tests for EBV have improved and are increasingly used in …

VZV T cell-mediated immunity

A Weinberg, MJ Levin - Varicella-Zoster Virus, 2010 - Springer
Primary varicella-zoster virus (VZV) infection (varicella) induces VZV-specific antibody and
VZV-specific T cell-mediated immunity. T cell-mediated immunity, which is detected within 1 …

Using Epstein-Barr viral load assays to diagnose, monitor, and prevent posttransplant lymphoproliferative disorder

ML Gulley, W Tang - Clinical Microbiology Reviews, 2010 - Am Soc Microbiol
SUMMARY Epstein-Barr virus (EBV) DNA measurement is being incorporated into routine
medical practice to help diagnose, monitor, and predict posttransplant lymphoproliferative …

High‐throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV‐reactive CD8+ T cells

A Lossius, JN Johansen, F Vartdal… - European journal of …, 2014 - Wiley Online Library
Epstein‐Barr virus (EBV) has long been suggested as a pathogen in multiple sclerosis (MS).
Here, we used high‐throughput sequencing to determine the diversity …

Diversity and divergence of the glioma-infiltrating T-cell receptor repertoire

JS Sims, B Grinshpun, Y Feng… - Proceedings of the …, 2016 - National Acad Sciences
Although immune signaling has emerged as a defining feature of the glioma
microenvironment, how the underlying structure of the glioma-infiltrating T-cell population …

Cytotoxic CD4+ T cell responses to EBV contrast with CD8 responses in breadth of lytic cycle antigen choice and in lytic cycle recognition

HM Long, AM Leese, OL Chagoury… - The Journal of …, 2011 - journals.aai.org
EBV, a B lymphotropic herpesvirus, encodes two immediate early (IE)-,> 30 early (E)-, and>
30 late (L)-phase proteins during its replication (lytic) cycle. Despite this, lytic Ag-induced …

Efficient culture of human naive and memory B cells for use as APCs

KY Su, A Watanabe, CH Yeh, G Kelsoe… - The Journal of …, 2016 - journals.aai.org
The ability to culture and expand B cells in vitro has become a useful tool for studying
human immunity. A limitation of current methods for human B cell culture is the capacity to …

EBV and MS: Major cause, minor contribution or red-herring?

S Burnard, J Lechner-Scott, RJ Scott - Multiple sclerosis and related …, 2017 - Elsevier
Multiple Sclerosis (MS) is a chronic neurological disease with genetic and environmental
risk factors. Epstein Barr-Virus (EBV) has been closely associated with MS but with a …

In vitro and in vivo evidence that the switch from calcineurin to mTOR inhibitors may be a strategy for immunosuppression in Epstein–Barr virus–associated post …

CJ Thieme, M Schulz, P Wehler, M Anft, L Amini… - Kidney International, 2022 - Elsevier
Post-transplant lymphoproliferative disorder is a life-threatening complication of
immunosuppression following transplantation mediated by failure of T cells to control …

Adoptive cell therapy against EBV-related malignancies: a survey of clinical results

A Merlo, R Turrini, R Dolcetti, P Zanovello… - Expert opinion on …, 2008 - Taylor & Francis
Background: Epstein–Barr Virus (EBV) infection is associated with a heterogeneous group
of tumors, including lymphoproliferative disorders, Hodgkin's disease, nasopharyngeal …