Colorectal cancer (CRC) is a global problem affecting millions of people worldwide. This
disease is unique because of its slow progress that makes it preventable and often curable …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Background: Several approaches have been suggested to be useful in the early detection of
colorectal neoplasms. Since metabolites are closely related to the phenotype and are …

Targeted detection is one of the most important methods in mass spectrometry (MS)-based
metabolomics; however, its major limitation is the reduced metabolome coverage that results …

The retinal pigment epithelium (RPE) is a monolayer of pigmented cells between the choroid
and the retina. RPE dysfunction underlies many retinal degenerative diseases, including …

Production of energy in a cell must keep pace with demand. Photoreceptors use ATP to
maintain ion gradients in darkness, whereas in light they use it to support phototransduction …

Background Low–glycemic load dietary patterns, characterized by consumption of whole
grains, legumes, fruits, and vegetables, are associated with reduced risk of several chronic …

Metabolic flux analysis (MFA) is highly relevant to understanding metabolic mechanisms of
various biological processes. While the pace of methodology development in MFA has been …

Creatinine is a well-stablished biomarker for kidney malfunctions and for normalization
parameter of urinary quantitative information. Recently, metabolic studies have been …

Traditional Chinese medicines (TCM) have a long history of use because of its potential
complementary therapy and fewer adverse effects. However, the toxicity and safety issues of …