Introduction: The etiology of atopic dermatitis (AD) is multifactorial with interaction between
genetics, immune and environmental factors. Areas covered: We review the role of prenatal …

The skin protects the body from unwanted influences from the environment as well as
excessive water loss. The barrier function of the skin is located in the stratum corneum (SC) …

The availability of allergen molecules ('components') from several protein families has
advanced our understanding of immunoglobulin E (IgE)‐mediated responses and enabled …

Background Interleukin (IL)-13 plays a key role in type 2 inflammation and is an emerging
pathogenic mediator in atopic dermatitis (AD). Objective We investigated the efficacy and …

Atopic dermatitis is a chronic inflammatory skin disease that affects 15–30% of children and
approximately 5% of adults in industrialized countries. Although the pathogenesis of atopic …

There is a growing desire to explain the worldwide rise in the prevalence of atopic dermatitis
(AD). Trend data on the burden of AD suggest that the picture in the developing world may …

Emollients and moisturisers for eczema - van Zuuren, EJ - 2017 | Cochrane Library Skip to
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Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an
immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose (1). It was …

Importance Atopic dermatitis is an inflammatory, pruritic skin disease that often occurs in
early infancy with a chronic course. However, a specific description of subtypes of atopic …

A hallmark of atopic eczema (AE) is skin barrier dysfunction. Lipids in the stratum corneum
(SC), primarily ceramides, fatty acids, and cholesterol, are crucial for the barrier function, but …