More than 200 studies and reports have been published regarding the use of
dexmedetomidine in infants and children. We reviewed the English literature to summarize …

Cardiac arrest occurs at a higher rate in children with heart disease than in healthy children.
Pediatric basic life support and advanced life support guidelines focus on delivering high …

Objective To investigate the safety, efficacy, and pharmacokinetic profile of
dexmedetomidine in preterm and full-term neonates≥ 28 to≤ 44 weeks gestational age …

Importance of the field: Dexmedetomidine is an α2-adrenoceptor agonist with sedative,
anxiolytic and analgesic properties. It is used off-label in pediatric patients due to its efficacy …

BACKGROUND: Dexmedetomidine is a highly selective α 2-agonist with hypnotic,
analgesic, and anxiolytic properties. Despite off-label administration, dexmedetomidine has …

Due to a favorable mix of beneficial physiologic actions and a limited adverse effect profile,
DEX is established in the perioperative pediatric cardiac surgery setting. However, evidence …

This study aimed to provide a general description of the cardiovascular and hemodynamic
effects of dexmedetomidine and an evidence-based review of the literature regarding its use …

BACKGROUND: Dexmedetomidine, an α-2 receptor agonist, is widely used in children with
cardiac disease. Significant hemodynamic responses, including systemic and pulmonary …

Arrhythmias are the common complications following cardiac surgery and contribute to
hemodynamic instability, cognitive impairment, thromboembolic events, and congestive …

This report aims to provide a general description of the cardiovascular effects of
dexmedetomidine, emphasizing its effects on conduction, and to give an evidence-based …