Behçet's disease: ocular effects and treatment

CME Deuter, I Kötter, GR Wallace, PI Murray… - Progress in retinal and …, 2008 - Elsevier
Behçet's disease (BD) is a systemic immune-mediated vasculitis of unclear origin. Major
symptoms include oral aphthous ulcers, genital ulcerations, skin lesions, and ocular lesions …

Ocular Behçet disease: current therapeutic approaches

C Evereklioglu - Current opinion in ophthalmology, 2011 - journals.lww.com
Biological agents offer tremendous potential in the treatment of OBD. Given that OBD
predominantly afflicts the younger adults in their most productive years, dermatologist …

Association of allelic variants of factor V Leiden, prothrombin and methylenetetrahydrofolate reductase with thrombosis or ocular involvement in Behçet's disease: a …

AJ Chamorro, M Marcos, I Hernández-García… - Autoimmunity …, 2013 - Elsevier
Thrombosis is frequent in patients with Behçet's disease (BD), although the exact cause
remains uncertain. Some single nucleotide polymorphism (SNP)(G1691A in factor V gene …

Serum homocysteine, vitamin B12, folic acid levels and methylenetetrahydrofolate reductase (MTHFR) gene polymorphism in vitiligo

A Yasar, K Gunduz, E Onur, M Calkan - Disease markers, 2012 - content.iospress.com
The aim of this study was to determine serum vitamin B12, folic acid and homocysteine (Hcy)
levels as well as MTHFR (C677, A1298C) gene polymorphisms in patients with vitiligo, and …

Influence of age at diagnosis and sex on clinical course and long-term prognosis of intestinal Behcet's disease

YS Jung, JY Yoon, SP Hong, TI Kim… - Inflammatory bowel …, 2012 - academic.oup.com
Background The aim of this study was to examine the influence of age at diagnosis and sex
on the clinical course and long-term prognosis of intestinal Behcet's disease (BD). Methods …

IL-4 and MTHFR gene polymorphism in rheumatoid arthritis and their effects

A Inanir, S Yigit, A Tekcan, S Tural, G Kismali - Immunology letters, 2013 - Elsevier
Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease that mainly affects the
joints. Polymorphic variations of the cytokine genes and MTHFR gene have received …

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and variations of homocysteine concentrations in patients with Behcet's disease

M Messedi, M Frigui, K Chaabouni, M Turki, M Neifer… - Gene, 2013 - Elsevier
Background Behcet's disease (BD) is a chronic, relapsing, multi-systemic inflammatory
disorder of unknown causes. This disease is mainly characterized by mucocutaneous …

Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome

A Inanir, S Yigit, A Tekcan, FA Pinarli, S Inanir… - Gene, 2015 - Elsevier
Objective Fibromyalgia syndrome (FM) is a common disease characterized by generalized
body pain, sensitivity in certain physical areas (sensitive points), lowered pain threshold …

Targeted resequencing of candidate genes reveals novel variants associated with severe Behçet's uveitis

SJ Kim, S Lee, C Park, JS Seo, JI Kim… - Experimental & molecular …, 2013 - nature.com
Behçet's disease (BD) is a chronic systemic inflammatory disorder characterized by four
major manifestations: recurrent uveitis, oral and genital ulcers and skin lesions. To identify …

Association between MTHFR variant and diabetic neuropathy

A Kakavand Hamidi, M Radfar, MM Amoli - Pharmacological Reports, 2018 - Springer
Background Methylene-tetrahydrofolate reductase (MTHFR) gene variant may play an
important role in the pathophysiology of diabetes and its complications due to its influence …