Starvation Responses Throughout the Caenorhabditis elegans Life Cycle
Caenorhabditis elegans survives on ephemeral food sources in the wild, and the species
has a variety of adaptive responses to starvation. These features of its life history make the …
has a variety of adaptive responses to starvation. These features of its life history make the …
From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural variation
Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …
a small number of genes and thereby molecular mechanisms have been discovered …
[PDF][PDF] Natural genetic variation as a tool for discovery in Caenorhabditis nematodes
EC Andersen, MV Rockman - Genetics, 2022 - academic.oup.com
Over the last 20 years, studies of Caenorhabditis elegans natural diversity have
demonstrated the power of quantitative genetic approaches to reveal the evolutionary …
demonstrated the power of quantitative genetic approaches to reveal the evolutionary …
Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles
SR Hahnel, S Zdraljevic, BC Rodriguez, Y Zhao… - PLoS …, 2018 - journals.plos.org
Benzimidazoles (BZ) are essential components of the limited chemotherapeutic arsenal
available to control the global burden of parasitic nematodes. The emerging threat of BZ …
available to control the global burden of parasitic nematodes. The emerging threat of BZ …
Experimental Evolution with Caenorhabditis Nematodes
The hermaphroditic nematode Caenorhabditis elegans has been one of the primary model
systems in biology since the 1970s, but only within the last two decades has this nematode …
systems in biology since the 1970s, but only within the last two decades has this nematode …
Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism
We find that variation in the dbt-1 gene underlies natural differences in Caenorhabditis
elegans responses to the toxin arsenic. This gene encodes the E2 subunit of the branched …
elegans responses to the toxin arsenic. This gene encodes the E2 subunit of the branched …
[PDF][PDF] Natural Variation in the Distribution and Abundance of Transposable Elements Across the Caenorhabditis elegans Species
KM Laricchia, S Zdraljevic, DE Cook… - … biology and evolution, 2017 - academic.oup.com
Transposons are mobile DNA elements that generate both adaptive and deleterious
phenotypic variation thereby driving genome evolution. For these reasons, genomes have …
phenotypic variation thereby driving genome evolution. For these reasons, genomes have …
A fln-2 mutation affects lethal pathology and lifespan in C. elegans
Differences in genetic background in model organisms can have complex effects on
phenotypes of interest. We previously reported a difference in hermaphrodite lifespan …
phenotypes of interest. We previously reported a difference in hermaphrodite lifespan …
Changes to social feeding behaviors are not sufficient for fitness gains of the Caenorhabditis elegans N2 reference strain
The standard reference Caenorhabditis elegans strain, N2, has evolved marked behavioral
changes in social feeding behavior since its isolation from the wild. We show that the causal …
changes in social feeding behavior since its isolation from the wild. We show that the causal …
Human Migration and the Spread of the Nematode Parasite Wuchereria bancrofti
The human disease lymphatic filariasis causes the debilitating effects of elephantiasis and
hydrocele. Lymphatic filariasis currently affects the lives of 90 million people in 52 countries …
hydrocele. Lymphatic filariasis currently affects the lives of 90 million people in 52 countries …