Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

Importance Chronic pelvic pain (CPP) is a challenging condition that affects an estimated
26% of the world's female population. Chronic pelvic pain accounts for 40% of …

Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and
synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central …

Centralized pain syndromes are associated with changes within the central nervous system
that amplify peripheral input and/or generate the perception of pain in the absence of a …

Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common
disorder in which the two main clinical features are pelvic pain and lower urinary tract …

Abstract Background Hypermobile Ehlers–Danlos syndrome (hEDS) and hypermobility
spectrum disorders (HSD) are debilitating conditions. Diagnosis is currently clinical in the …

Mechanisms underlying chronic pain differ from those underlying acute pain. In chronic pain
states, central nervous system (CNS) factors appear to play particularly prominent roles. In …

BACKGROUND Chronic pelvic pain (CPP) is a significant public health problem with 1
million affected women in the UK. Although many pathologies are associated with CPP, the …

Aims Terms used in the field of chronic pelvic pain (CPP) are poorly defined and often
confusing. An International Continence Society (ICS) Standard for Terminology in chronic …

As the biological alarm of impending or actual tissue damage, pain is essential for our
survival. However, when it is initiated and/or sustained by dysfunctional elements in the …