Induction of heat shock proteins for protection against oxidative stress
B Kalmar, L Greensmith - Advanced drug delivery reviews, 2009 - Elsevier
Heat shock proteins (Hsps) have been studied for many years and there is now a large body
of evidence that demonstrates the role of Hsp upregulation in tissue and cell protection in a …
of evidence that demonstrates the role of Hsp upregulation in tissue and cell protection in a …
Heat shock proteins: cellular and molecular mechanisms in the central nervous system
Emerging evidence indicates that heat shock proteins (HSPs) are critical regulators in
normal neural physiological function as well as in cell stress responses. The functions of …
normal neural physiological function as well as in cell stress responses. The functions of …
Structure and function of the small heat shock protein/α-crystallin family of molecular chaperones
R Van Montfort, C Slingsby, E Vierlingt - Advances in protein chemistry, 2001 - Elsevier
Publisher Summary The goal of this chapter is to clarify the diversity within the heat shock
proteins (sHsps) family and to describe evidence indicating that sHsps have many different …
proteins (sHsps) family and to describe evidence indicating that sHsps have many different …
Multiple molecular penumbras after focal cerebral ischemia
FR Sharp, A Lu, Y Tang… - Journal of Cerebral Blood …, 2000 - journals.sagepub.com
Though the ischemic penumbra has been classically described on the basis of blood flow
and physiologic parameters, a variety of ischemic penumbras can be described in molecular …
and physiologic parameters, a variety of ischemic penumbras can be described in molecular …
Identification of ischemic regions in a rat model of stroke
Background Investigations following stroke first of all require information about the spatio-
temporal dimension of the ischemic core as well as of perilesional and remote affected …
temporal dimension of the ischemic core as well as of perilesional and remote affected …
High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1
Z Batulan, GA Shinder, S Minotti, BP He… - Journal of …, 2003 - Soc Neuroscience
Heat shock protein 70 (Hsp70) protects cultured motor neurons from the toxic effects of
mutations in Cu/Zn-superoxide dismutase (SOD-1), which is responsible for a familial form of …
mutations in Cu/Zn-superoxide dismutase (SOD-1), which is responsible for a familial form of …
The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system
TB Franklin, AM Krueger-Naug, DB Clarke… - International Journal …, 2005 - Taylor & Francis
Heat shock proteins (Hsps) are highly conserved and under physiological conditions act as
molecular chaperones and/or have anti-apoptotic activities. Expression in the brain of two …
molecular chaperones and/or have anti-apoptotic activities. Expression in the brain of two …
Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes
G Tezel, MR Hernandez, MB Wax - Archives of ophthalmology, 2000 - jamanetwork.com
Purpose To examine immunostaining of 60-kd and 27-kd heat shock proteins (HSP 60 and
HSP 27), which are known to increase cell survival in response to stress, in glaucomatous …
HSP 27), which are known to increase cell survival in response to stress, in glaucomatous …
Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning
G Xi, RF Keep, Y Hua, J Xiang, JT Hoff - Stroke, 1999 - Am Heart Assoc
Background and Purpose—Edema formation after intracerebral hemorrhage has been
linked to thrombin toxicity induced by the clot. However, thrombin at low concentrations …
linked to thrombin toxicity induced by the clot. However, thrombin at low concentrations …
Heat shock protein 27: developmental regulation and expression after peripheral nerve injury
M Costigan, RJ Mannion, G Kendall… - Journal of …, 1998 - Soc Neuroscience
The heat shock protein (HSP) 27 is constitutively expressed at low levels in medium-sized
lumbar dorsal root ganglion (DRG) cells in adult rats. Transection of the sciatic nerve results …
lumbar dorsal root ganglion (DRG) cells in adult rats. Transection of the sciatic nerve results …