Current and novel biomarkers of thrombotic risk in COVID-19: a consensus statement from the international COVID-19 thrombosis biomarkers colloquium

DA Gorog, RF Storey, PA Gurbel, US Tantry… - Nature Reviews …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and
thromboembolic events, owing to excessive inflammation, endothelial cell activation and …

Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …

Interplay between inflammation and thrombosis in cardiovascular pathology

K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps

JM Adrover, SAC McDowell, XY He, DF Quail… - Cancer Cell, 2023 - cell.com
Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

M Merad, JC Martin - Nature reviews immunology, 2020 - nature.com
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …

Signaling pathways and intervention therapies in sepsis

Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

[HTML][HTML] Targeting potential drivers of COVID-19: Neutrophil extracellular traps

BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
Disclosures: MR Looney reported" other" from Neutrolis outside the submitted work. RE
Schwartz is a Sponsored Advisory Board Member for Miromatrix Inc. JD Spicer reported …

Patients with COVID-19: in the dark-NETs of neutrophils

M Ackermann, HJ Anders, R Bilyy, GL Bowlin… - Cell Death & …, 2021 - nature.com
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

Vascular occlusion by neutrophil extracellular traps in COVID-19

M Leppkes, J Knopf, E Naschberger, A Lindemann… - …, 2020 - thelancet.com
Background Coronavirus induced disease 2019 (COVID-19) can be complicated by severe
organ damage leading to dysfunction of the lungs and other organs. The processes that …

Neutrophil extracellular traps: from physiology to pathology

A Hidalgo, P Libby, O Soehnlein… - Cardiovascular …, 2022 - academic.oup.com
At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …