Design of pressure-driven microfluidic networks using electric circuit analogy

KW Oh, K Lee, B Ahn, EP Furlani - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …

Microfluidic blood cell sorting: now and beyond

ZTF Yu, KM Aw Yong, J Fu - Small, 2014 - Wiley Online Library
Blood plays an important role in homeostatic regulation with each of its cellular components
having important therapeutic and diagnostic uses. Therefore, separation and sorting of …

Recent advances in microfluidic platform for physical and immunological detection and capture of circulating tumor cells

MP Bhat, V Thendral, UT Uthappa, KH Lee, M Kigga… - Biosensors, 2022 - mdpi.com
CTCs (circulating tumor cells) are well-known for their use in clinical trials for tumor
diagnosis. Capturing and isolating these CTCs from whole blood samples has enormous …

A microfluidic device for simultaneous extraction of plasma, red blood cells, and on-chip white blood cell trapping

DH Kuan, CC Wu, WY Su, NT Huang - Scientific reports, 2018 - nature.com
This study reports a microfluidic device for whole blood processing. The device uses the
bifurcation law, cross-flow method, and hydrodynamic flow for simultaneous extraction of …

Rapid and effective enrichment of mononuclear cells from blood using acoustophoresis

A Urbansky, P Ohlsson, A Lenshof, F Garofalo… - Scientific reports, 2017 - nature.com
Effective separation methods for fractionating blood components are needed for numerous
diagnostic and research applications. This paper presents the use of acoustophoresis, an …

High-throughput particle manipulation based on hydrodynamic effects in microchannels

C Liu, G Hu - Micromachines, 2017 - mdpi.com
Microfluidic techniques are effective tools for precise manipulation of particles and cells,
whose enrichment and separation is crucial for a wide range of applications in biology …

A simple microfluidic device for the deformability assessment of blood cells in a continuous flow

RO Rodrigues, D Pinho, V Faustino, R Lima - Biomedical microdevices, 2015 - Springer
Blood flow presents several interesting phenomena in microcirculation that can be used to
develop microfluidic devices capable to promote blood cells separation and analysis in …

Extracting white blood cells from blood on microfluidics platform: a review of isolation techniques and working mechanisms

V Laxmi, SS Joshi, A Agrawal - Journal of Micromechanics and …, 2022 - iopscience.iop.org
Selective isolation of human blood cells has numerous applications in disease diagnostic,
prognostics, drug discovery, and drug delivery. In particular, isolation of white blood cells …

On-chip extraction of intracellular molecules in white blood cells from whole blood

J Choi, J Hyun, S Yang - Scientific reports, 2015 - nature.com
The extraction of virological markers in white blood cells (WBCs) from whole blood—without
reagents, electricity, or instruments—is the most important first step for diagnostic testing of …

Inertial microfluidics combined with selective cell lysis for high throughput separation of nucleated cells from whole blood

H Ramachandraiah, HA Svahn, A Russom - RSC advances, 2017 - pubs.rsc.org
The ability to rapidly analyze and extract information from peripheral blood cells has the
potential of providing a wealth of new information about immune function and general health …