Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

G protein‐coupled receptors (GPCRs) and heterotrimeric G proteins play central roles in a
diverse array of cellular processes. As such, dysregulation of GPCRs and their coupled …

Glioblastoma, a subset of aggressive brain tumors, deploy several means to increase blood
vessel supply dedicated to the tumor mass. This includes typical program borrowed from …

Apelin, an endogenous ligand for the G protein-coupled receptor APJ, is extensively
expressed in various systems, especially the nervous system. This article reviews the role of …

Cancer is a disease that seriously endangers human health and is mainly characterized by
a high metastasis rate, a high recurrence rate, and a high mortality rate. The treatment of …

Apelin, a peptide initially isolated from bovine stomach extract, is an endogenous ligand for
the Apelin Receptor (APLNR). Subsequently, a second peptide, ELABELA, that can bind to …

Lipo-oligomers, post-functionalized with ligands to enhance targeting, represent promising
new vehicles for the tumor-specific delivery of therapeutic genes such as the sodium iodide …

Although mesenchymal stem cell‐(MSC‐) based therapy has shown promising results for
myocardial infarction (MI), low cell survival heavily limits its beneficial effects. Apelin plays …

Apelin is an endogenous ligand that binds to the G protein-coupled receptor angiotensin-
like-receptor 1 (APJ). Apelin and APJ are widely distributed in organs and tissues and are …

Apelin (APLN) is an endogenous ligand of the G protein-coupled receptor APJ (APLNR).
APLN has been implicated in the development of multiple tumours. Herein, we determined …