A visual and comprehensive review on COVID-19-associated pulmonary aspergillosis (CAPA)

S Feys, MP Almyroudi, R Braspenning, K Lagrou… - Journal of Fungi, 2021 - mdpi.com
Coronavirus disease 19 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a severe
fungal infection complicating critically ill COVID-19 patients. Numerous retrospective and …

COVID-19 at a glance: An up-to-date overview on variants, drug design and therapies

D Iacopetta, J Ceramella, A Catalano, C Saturnino… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the
Coronavirus family which caused the worldwide pandemic of human respiratory illness …

Virtual screening and molecular dynamics simulations provide insight into repurposing drugs against SARS-CoV-2 variants Spike protein/ACE2 interface

D Pirolli, B Righino, C Camponeschi, F Ria… - Scientific Reports, 2023 - nature.com
After over two years of living with Covid-19 and hundreds of million cases worldwide there is
still an unmet need to find proper treatments for the novel coronavirus, due also to the rapid …

Antifungal drugs TDM: trends and update

B Kably, M Launay, A Derobertmasure… - Therapeutic Drug …, 2022 - journals.lww.com
Purpose: The increasing burden of invasive fungal infections results in growing challenges
to antifungal (AF) therapeutic drug monitoring (TDM). This review aims to provide an …

Inhaled ciclesonide for outpatient treatment of COVID-19 in adults at risk of adverse outcomes: a randomised controlled trial (COVERAGE)

A Duvignaud, E Lhomme, R Onaisi, R Sitta… - Clinical Microbiology …, 2022 - Elsevier
Objectives To assess the efficacy of inhaled ciclesonide in reducing the risk of adverse
outcomes in COVID-19 outpatients at risk of developing severe illness. Methods …

Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples

A Biji, O Khatun, S Swaraj, R Narayan, RS Rajmani… - …, 2021 - thelancet.com
Background While our battle with the COVID-19 pandemic continues, a multitude of Omics
data have been generated from patient samples in various studies. Translation of these data …

In vitro activity of itraconazole against SARS‐CoV‐2

E Van Damme, S De Meyer, D Bojkova… - Journal of medical …, 2021 - Wiley Online Library
Although vaccination campaigns are currently being rolled out to prevent coronavirus
disease (COVID‐19), antivirals will remain an important adjunct to vaccination. Antivirals …

Lipid compartments and lipid metabolism as therapeutic targets against coronavirus

D Cesar-Silva, FS Pereira-Dutra, ALM Giannini… - Frontiers in …, 2023 - frontiersin.org
Lipids perform a series of cellular functions, establishing cell and organelles' boundaries,
organizing signaling platforms, and creating compartments where specific reactions occur …

[HTML][HTML] β-Cyclodextrins as affordable antivirals to treat coronavirus infection

D Raïch-Regué, R Tenorio, IF de Castro… - Biomedicine & …, 2023 - Elsevier
The SARS-CoV-2 pandemic made evident that there are only a few drugs against
coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity …

The need for speed and efficiency: a brief review of small molecule antivirals for COVID-19

AC Puhl, TR Lane, F Urbina, S Ekins - Frontiers in Drug Discovery, 2022 - frontiersin.org
While we currently have multiple highly effective vaccines approved for use against SARS-
CoV-2 in the USA and other countries, there are far fewer small molecule antivirals …