Glucocorticoids are primary stress hormones necessary for life that regulate numerous
physiologic processes in an effort to maintain homeostasis. Synthetic derivatives of these …

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into several
tissues, such as bone, cartilage, and fat. Glucocorticoids affect a variety of biological …

Glucocorticoid resistance or insensitivity is a major barrier to the treatment of several
common inflammatory diseases—including chronic obstructive pulmonary disease and …

Hyperactivity of the hypothalamus–pituitary–adrenal (HPA) axis and increased levels of
glucocorticoid hormones in patients with depression have mostly been ascribed to impaired …

Patients with multiple myeloma (MM) carrying standard-or high-risk cytogenetic
abnormalities (CAs) achieve similar complete response (CR) rates, but the later have inferior …

BACKGROUND The use of antenatal steroid therapy is common in pregnancy. In early
pregnancy, steroids may be used in women for the treatment of recurrent miscarriage or fetal …

Glucocorticoids regulate numerous physiological processes and are mainstays in the
treatment of inflammation, autoimmune disease, and cancer. The traditional view that …

The glucocorticoid receptor is a member of the nuclear receptor family that controls many
distinct gene networks, governing various aspects of development, metabolism …

Glucocorticoids are steroid hormones that regulate diverse cellular functions and are
essential to facilitate normal physiology. However, stress-induced levels of glucocorticoids …

Glucocorticoids are a vital class of endogenous steroid hormones that regulate essential
biological processes including growth, development, metabolism, behavior and apoptosis …