Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of
disorders characterized by early-onset, often severe epileptic seizures and EEG …

From an evolutionary perspective keratan sulfate (KS) is the newest glycosaminoglycan
(GAG) but the least understood. KS is a sophisticated molecule with a diverse structure, and …

Oligomannosidic glycans play important roles in nervous system development and function.
By performing a phage display screening with oligomannose-specific antibodies, we …

Synapsins serve as flagships among the presynaptic proteins due to their abundance on
synaptic vesicles and contribution to synaptic communication. Several studies have …

Synaptopathies are a class of neurodevelopmental disorders caused by modification in
genes coding for synaptic proteins. These proteins oversee the process of …

The pathology of traumatic brain injury (TBI) is characterized by the decreased capacity of
neurons to metabolize energy and sustain synaptic function, likely resulting in cognitive and …

Exercise is known to improve cognitive functions and to induce neuroprotection. In this study
we used a short-term, moderate intensity treadmill exercise protocol to investigate the effects …

Background Developmental processes in the placenta and the fetal brain are shaped by the
same biological signals. Recent evidence suggests that adaptive responses of the placenta …

During development, pyramidal neurons undergo dynamic regulation of AMPA receptor
(AMPAR) subunit composition and density to help drive synaptic plasticity and maturation …

Gangliosides play vital biological regulatory roles and are associated with neurological
system diseases, malignancies, and immune deficiencies. They have received extensive …