Potential role of mitochondria-associated endoplasmic reticulum membrane proteins in diseases
H Mao, W Chen, L Chen, L Li - Biochemical pharmacology, 2022 - Elsevier
Mitochondria-associated endoplasmic reticulum membranes (MAMs) are dynamic
membrane coupling regions formed by the coupling of the mitochondrial outer membrane …
membrane coupling regions formed by the coupling of the mitochondrial outer membrane …
Subcellular visualization: organelle-specific targeted drug delivery and discovery
Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …
and internal environment. Disorders in organelles or their interacting networks have been …
Emerging translational research in neurological and psychiatric diseases: From in vitro to in vivo models
Revealing the underlying pathomechanisms of neurological and psychiatric disorders,
searching for new biomarkers, and developing novel therapeutics all require translational …
searching for new biomarkers, and developing novel therapeutics all require translational …
Neural correlates and molecular mechanisms of memory and learning
Memory and learning are essential cognitive processes that enable us to obtain, retain, and
recall information. These factors are crucial for survival, adaptation, and creativity. However …
recall information. These factors are crucial for survival, adaptation, and creativity. However …
ER‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein
Abnormal tau protein impairs mitochondrial function, including transport, dynamics, and
bioenergetics. Mitochondria interact with the endoplasmic reticulum (ER) via mitochondria …
bioenergetics. Mitochondria interact with the endoplasmic reticulum (ER) via mitochondria …
The ER-mitochondria interface, where Ca2+ and cell death meet
I de Ridder, M Kerkhofs, FO Lemos, J Loncke… - Cell calcium, 2023 - Elsevier
Endoplasmic reticulum (ER)-mitochondria contact sites are crucial to allow Ca 2+ flux
between them and a plethora of proteins participate in tethering both organelles together …
between them and a plethora of proteins participate in tethering both organelles together …
Disentangling mitochondria in Alzheimer's disease
A Johri - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …
a major societal and economic burden due to an increase in life expectancy. Age seems to …
Endoplasmic reticulum-mitochondria contacts modulate reactive oxygen species-mediated signaling and oxidative stress in brain disorders: The key role of sigma-1 …
R Resende, T Fernandes, AC Pereira… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Mitochondria-Associated Membranes (MAMs) are highly dynamic endoplasmic
reticulum (ER)-mitochondria contact sites that, due to the transfer of lipids and Ca2+ …
reticulum (ER)-mitochondria contact sites that, due to the transfer of lipids and Ca2+ …
The regulatory role of adipocyte mitochondrial homeostasis in metabolism-related diseases
H Song, X Zhang, J Wang, Y Wu, T Xiong… - Frontiers in …, 2023 - frontiersin.org
Adipose tissue is the most important energy storage organ in the body, maintaining its
normal energy metabolism function and playing a vital role in keeping the energy balance of …
normal energy metabolism function and playing a vital role in keeping the energy balance of …
Hippocampal GFAP-positive astrocyte responses to amyloid and tau pathologies
Abstract Introduction In Alzheimer's disease clinical research, glial fibrillary acidic protein
(GFAP) released/leaked into the cerebrospinal fluid and blood is widely measured and …
(GFAP) released/leaked into the cerebrospinal fluid and blood is widely measured and …