Implication of intestinal barrier dysfunction in gut dysbiosis and diseases
The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …
Probiotics and gut microbiota: Mechanistic insights into gut immune homeostasis through TLR pathway regulation
Consumption of probiotics as a useful functional food improves the host's wellbeing, and,
when paired with prebiotics (indigestible dietary fibre/carbohydrate), often benefits the host …
when paired with prebiotics (indigestible dietary fibre/carbohydrate), often benefits the host …
Stem cell-derived intestinal organoids: a novel modality for IBD
C Tian, M Yang, H Xu, M Zhu, NN Yue, Y Zhang… - Cell Death …, 2023 - nature.com
The organoids represent one of the greatest revolutions in the biomedical field in the past
decade. This three-dimensional (3D) micro-organ cultured in vitro has a structure highly …
decade. This three-dimensional (3D) micro-organ cultured in vitro has a structure highly …
The intestinal barrier—shielding the body from nano-and microparticles in our diet
M Schwarzfischer, G Rogler - Metabolites, 2022 - mdpi.com
Nano-and microparticles are an implicit part of the human diet. They are unknowingly
ingested with our food that contains them as additives or pollutants. However, their impact …
ingested with our food that contains them as additives or pollutants. However, their impact …
The epithelial barrier theory: development and exacerbation of allergic and other chronic inflammatory diseases
It is now longer than half a century, humans, animals, and nature of the world are under the
influence of exposure to many newly introduced noxious substances. These exposures are …
influence of exposure to many newly introduced noxious substances. These exposures are …
Exploring potential biomarkers and therapeutic targets in inflammatory bowel disease: insights from a mega-analysis approach
E Stemmer, T Zahavi, M Kellerman… - Frontiers in …, 2024 - frontiersin.org
Background Understanding the molecular pathogenesis of inflammatory bowel disease
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …
Ocular instillation of conditioned medium from mesenchymal stem cells is effective for dry eye syndrome by improving corneal barrier function
T Imaizumi, R Hayashi, Y Kudo, X Li, K Yamaguchi… - Scientific Reports, 2023 - nature.com
Dry eye syndrome (DES) is a chronic ocular disease that induces epithelial damage to the
cornea by decreasing tear production and quality. Adequate treatment options have not …
cornea by decreasing tear production and quality. Adequate treatment options have not …
Monotropein inhibits colitis associated cancer through VDR/JAK1/STAT1 regulation of macrophage polarization
Y Lu, Y Chen, Y Li, S Xu, D Lian, J Liang… - International …, 2023 - Elsevier
Colorectal cancer (CRC) is a growing concern due to its high morbidity and mortality, and
the search for effective and less toxic active substances against inflammatory bowel …
the search for effective and less toxic active substances against inflammatory bowel …
A proteomic insight reveals the role of food-associated Lactiplantibacillus plantarum C9O4 in reverting intestinal inflammation
Nowadays, Western diets and lifestyle lead to an increasing occurrence of chronic gut
inflammation that represents an emerging health concern with still a lack of successful …
inflammation that represents an emerging health concern with still a lack of successful …
[HTML][HTML] Patient-derived organoids for therapy personalization in inflammatory bowel diseases
M Lucafò, A Muzzo, M Marcuzzi, L Giorio… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders of the intestinal tract
that have emerged as a growing problem in industrialized countries. Knowledge of IBD …
that have emerged as a growing problem in industrialized countries. Knowledge of IBD …