[HTML][HTML] The pathomechanism, antioxidant biomarkers, and treatment of oxidative stress-related eye diseases
Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …
diseases. To provide a better understanding of the mechanism and treatment of …
Corticosteroids in ophthalmology: Drug delivery innovations, pharmacology, clinical applications, and future perspectives
SA Gaballa, UB Kompella, O Elgarhy… - Drug Delivery and …, 2021 - Springer
Corticosteroids remain the mainstay of the treatment for various ocular conditions affecting
the ocular surface, anterior and posterior segments of the eye due to their anti-inflammatory …
the ocular surface, anterior and posterior segments of the eye due to their anti-inflammatory …
Polymeric long-acting drug delivery systems (LADDS) for treatment of chronic diseases: Inserts, patches, wafers, and implants
Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …
precisely delivering drug molecules into target tissues either through the systemic circulation …
Biology of inherited cataracts and opportunities for treatment
A Shiels, JF Hejtmancik - Annual review of vision science, 2019 - annualreviews.org
Cataract, the clinical correlate of opacity or light scattering in the eye lens, is usually caused
by the presence of high-molecular-weight (HMW) protein aggregates or disruption of the …
by the presence of high-molecular-weight (HMW) protein aggregates or disruption of the …
[HTML][HTML] Role of oxidative stress in ocular diseases: a balancing act
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …
[HTML][HTML] Posterior segment ophthalmic drug delivery: Role of muco-adhesion with a special focus on chitosan
AM Burhan, B Klahan, W Cummins, V Andrés-Guerrero… - Pharmaceutics, 2021 - mdpi.com
Posterior segment eye diseases (PSEDs) including age macular degeneration (AMD) and
diabetic retinopathy (DR) are amongst the major causes of irreversible blindness worldwide …
diabetic retinopathy (DR) are amongst the major causes of irreversible blindness worldwide …
An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …
Age‐dependent changes in glutathione metabolism pathways in the lens: new insights into therapeutic strategies to prevent cataract formation—a review
Ocular tissues possess a robust antioxidant defence system to minimize oxidative stress and
preserve tissue structure and function. Glutathione (GSH) is a powerful antioxidant and in …
preserve tissue structure and function. Glutathione (GSH) is a powerful antioxidant and in …
[HTML][HTML] Pharmacological treatment strategies of pterygium: drugs, biologics, and novel natural products
SS Baheran, RG Alany, S Schwikkard, W Muen… - Drug Discovery …, 2023 - Elsevier
Pterygium is a fibrovascular tissue growth invading the cornea. Adjunctive treatment post-
surgery includes conventional immunosuppressants as well as antiviral drugs. The use of …
surgery includes conventional immunosuppressants as well as antiviral drugs. The use of …
[HTML][HTML] Emerging important roles of circRNAs in human cancer and other diseases
Y Huang, C Zhang, J Xiong, H Ren - Genes & diseases, 2021 - Elsevier
CircRNAs are a large class of endogenous single-stranded RNA that is different from other
linear RNA, which are produced by back-splicing and fusion of either exons, introns, or both …
linear RNA, which are produced by back-splicing and fusion of either exons, introns, or both …