Phase separation is a thermodynamic process leading to the formation of compositionally
distinct phases. For the past few years, numerous works have shown that biomolecular …

The aggregation of alpha-synuclein (aSyn) represents a neuropathological hallmark
observed in a group of neurodegenerative disorders collectively known as …

The etiology of Parkinson's disease is poorly understood and is most commonly associated
with advancing age, genetic predisposition, or environmental toxins. Epidemiological …

Alpha-synuclein (aSyn) pathology is present in approximately 50% of Alzheimer's disease
(AD) cases at autopsy and might impact the age-of-onset and disease progression in AD …

Synaptic vesicle (SV) clusters, which reportedly result from synapsin's capacity to undergo
liquid-liquid phase separation (LLPS), constitute the structural basis for neurotransmission …

Bacterial cells were long thought to be" bags of enzymes" with minimal internal structures. In
recent years, membrane-less organelles formed by liquid-liquid phase separation (LLPS) of …

How functional amyloids are regulated to restrict their activity is poorly understood. The
cytoplasmic polyadenylation element-binding protein 3 (CPEB3) is an RNA-binding protein …

Over the past decade, myriads of studies have highlighted the central role of protein
condensation in subcellular compartmentalization and spatiotemporal organization of …

Numerous proteins can undergo liquid-liquid phase separation (LLPS) in various biological
processes. However, it remains a challenge to systematically evaluate the LLPS ability of …

Taurine is a compatible osmolyte that confers stability to proteins. Recent studies have
revealed that liquid–liquid phase separation (LLPS) of proteins underlie the formation of …