Influence of hypoxia on the epithelial-pathogen interactions in the lung: implications for respiratory disease

LK Page, KJ Staples, CM Spalluto, A Watson… - Frontiers in …, 2021 - frontiersin.org
Under normal physiological conditions, the lung remains an oxygen rich environment.
However, prominent regions of hypoxia are a common feature of infected and inflamed …

Role of acute exacerbations in skeletal muscle impairment in COPD

HR Gosker, RC Langen, SO Simons - Expert Review of Respiratory …, 2021 - Taylor & Francis
Introduction: Muscle impairments are prevalent in COPD and have adverse clinical
implications in terms of physical performance capacity, disease burden, quality of life and …

The morphogenic protein CopD controls the spatio-temporal dynamics of PBP1a and PBP2b in Streptococcus pneumoniae

C Lenoir, A Pelletier, S Manuse, H Millat, A Ducret… - Mbio, 2023 - Am Soc Microbiol
Penicillin-binding proteins (PBPs) are key to the assembly of peptidoglycan, the major
component of the bacterial cell wall. Although several PBP-specific regulatory proteins have …

Circulating bacterial DNA as plasma biomarkers for lung cancer early detection

H Zhou, J Liao, Q Leng, M Chinthalapally… - Microorganisms, 2023 - mdpi.com
Simple Summary Pathogenic bacteria play a crucial role in tumor development. Our study
analyzed the presence of bacteria related to lung cancer in lung tumors, normal lung tissues …

Streptococcus pneumoniae promotes lung cancer development and progression

N Li, H Zhou, VK Holden, J Deepak, P Dhilipkannah… - Iscience, 2023 - cell.com
Streptococcus pneumoniae (SP) is associated with lung cancer, yet its role in the
tumorigenesis remains uncertain. Herein we find that SP attaches to lung cancer cells via …

COX-2/sEH-Mediated Macrophage Activation Is a Target for Pulmonary Protection in Mouse Models of Chronic Obstructive Pulmonary Disease

JX Duan, XX Guan, W Cheng, DD Deng, P Chen… - Laboratory …, 2024 - Elsevier
Effective inhibition of macrophage activation is critical for resolving inflammation and
restoring pulmonary function in patients with chronic obstructive pulmonary disease (COPD) …

Chronic obstructive pulmonary disease and cigarette smoke lead to dysregulated mucosal-associated invariant t-cell activation

ME Huber, E Larson, TN Lust, CM Heisler… - American journal of …, 2023 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is associated with airway inflammation,
increased infiltration by CD8+ T lymphocytes, and infection-driven exacerbations. Although …

Animal models of chronic obstructive pulmonary disease: a systematic review

T Feng, J Cao, X Ma, X Wang, X Guo, N Yan… - Frontiers in …, 2024 - frontiersin.org
Objective Experimental animal models have been used for decades to study the
development and progression of chronic obstructive pulmonary disease (COPD). However …

The associations between body composition and vital capacity index of medical students in Shenyang of China: a cross-sectional survey

H Zhang, L Sun, Y Yu, H Xin, L Wu, F Yang, J Liu… - BMC Pulmonary …, 2022 - Springer
Objectives This study aimed to examine the associations between body composition and
vital capacity index (VCI) among medical students of Shenyang, China. Study design The …

[PDF][PDF] 口腔菌群对肺部菌群的塑造介导的炎症反应与呼吸系统疾病关系的研究进展

吴珂, 付跃峰, 林龙, 莫名月, 黄泽娜, 林燕… - 中国微生态学 …, 2024 - cjm.dmu.edu.cn
菌群平衡对机体维持健康非常重要, 过去人们重点关注肠道菌群的失衡与疾病的关系,
肠道菌群与人体健康的相关研究全面而深入. 早期肺部被认为是无菌的, 人们未关注肺部菌群 …