Near-infrared luminescence high-contrast in vivo biomedical imaging

Y Chen, S Wang, F Zhang - Nature Reviews Bioengineering, 2023 - nature.com
Luminescence imaging in biomedical research has allowed new insights into the
architecture of pathological tissues, signalling networks and cell interactions, and is now …

Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Versatile types of inorganic/organic NIR-IIa/IIb fluorophores: from strategic design toward molecular imaging and theranostics

Y Liu, Y Li, S Koo, Y Sun, Y Liu, X Liu, Y Pan… - Chemical …, 2021 - ACS Publications
In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables
us to look deeply into living subjects, is producing marvelous opportunities for biomedical …

In vivo non-invasive confocal fluorescence imaging beyond 1,700 nm using superconducting nanowire single-photon detectors

F Wang, F Ren, Z Ma, L Qu, R Gourgues, C Xu… - Nature …, 2022 - nature.com
Light scattering by biological tissues sets a limit to the penetration depth of high-resolution
optical microscopy imaging of live mammals in vivo. An effective approach to reduce light …

Fundamentals and developments in fluorescence-guided cancer surgery

JSD Mieog, FB Achterberg, A Zlitni… - Nature reviews Clinical …, 2022 - nature.com
Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

Advanced fluorescence imaging technology in the near-infrared-II window for biomedical applications

C Li, G Chen, Y Zhang, F Wu… - Journal of the American …, 2020 - ACS Publications
Fluorescence imaging has become a fundamental tool for biomedical applications;
nevertheless, its intravital imaging capacity in the conventional wavelength range (400–950 …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …

Management of fluorescent organic/inorganic nanohybrids for biomedical applications in the NIR-II region

B Li, M Zhao, J Lin, P Huang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Biomedical fluorescence imaging in the second near-infrared (NIR-II, 100–1700 nm) window
provides great potential for visualizing physiological and pathological processes, owing to …

Room‐temperature phosphorescence resonance energy transfer for construction of near‐infrared afterglow imaging agents

Q Dang, Y Jiang, J Wang, J Wang, Q Zhang… - Advanced …, 2020 - Wiley Online Library
Afterglow imaging that detects photons after cessation of optical excitation avoids tissue
autofluorescence and thus possesses higher sensitivity than traditional fluorescence …