[HTML][HTML] Prenatal stressors in rodents: Effects on behavior
M Weinstock - Neurobiology of stress, 2017 - Elsevier
The current review focuses on studies in rodents published since 2008 and explores
possible reasons for any differences they report in the effects of gestational stress on various …
possible reasons for any differences they report in the effects of gestational stress on various …
Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics
Despite 50+ years of drug discovery, current antipsychotics have limited efficacy against
negative and cognitive symptoms of schizophrenia, and are ineffective—with the exception …
negative and cognitive symptoms of schizophrenia, and are ineffective—with the exception …
A comprehensive approach to modeling maternal immune activation in rodents
MC Bucknor, A Gururajan, RC Dale… - Frontiers in …, 2022 - frontiersin.org
Prenatal brain development is a highly orchestrated process, making it a very vulnerable
window to perturbations. Maternal stress and subsequent inflammation during pregnancy …
window to perturbations. Maternal stress and subsequent inflammation during pregnancy …
Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring
In utero and early neonatal exposure to maternal stress is linked with psychiatric disorders,
and the underlying mechanisms are currently being elucidated. We used a prenatal stressor …
and the underlying mechanisms are currently being elucidated. We used a prenatal stressor …
Cognitive dysfunction in major depressive disorder. A translational review in animal models of the disease
F Darcet, AM Gardier, R Gaillard, DJ David… - Pharmaceuticals, 2016 - mdpi.com
Major Depressive Disorder (MDD) is the most common psychiatric disease, affecting millions
of people worldwide. In addition to the well-defined depressive symptoms, patients suffering …
of people worldwide. In addition to the well-defined depressive symptoms, patients suffering …
Maternal distress and offspring neurodevelopment: challenges and opportunities for pre-clinical research models
E Fitzgerald, C Parent, MZL Kee… - Frontiers in Human …, 2021 - frontiersin.org
Pre-natal exposure to acute maternal trauma or chronic maternal distress can confer
increased risk for psychiatric disorders in later life. Acute maternal trauma is the result of …
increased risk for psychiatric disorders in later life. Acute maternal trauma is the result of …
Maternal programming of sex-specific responses to predator odor stress in adult rats
Prenatal stress mediated through the mother can lead to long-term adaptations in stress-
related phenotypes in offspring. This study tested the long-lasting effect of prenatal exposure …
related phenotypes in offspring. This study tested the long-lasting effect of prenatal exposure …
Sex-dependence and comorbidities of the early-life adversity induced mental and metabolic disease risks: Where are we at?
K Reemst, SR Ruigrok, L Bleker, EFG Naninck… - Neuroscience & …, 2022 - Elsevier
Early-life adversity (ELA) is a major risk factor for developing later-life mental and metabolic
disorders. However, if and to what extent ELA contributes to the comorbidity and sex …
disorders. However, if and to what extent ELA contributes to the comorbidity and sex …
Therapeutic inducers of the HSP 70/HSP 110 protect mice against traumatic brain injury
B Eroglu, DE Kimbler, J Pang, J Choi… - Journal of …, 2014 - Wiley Online Library
Traumatic brain injury (TBI) induces severe harm and disability in many accident victims and
combat‐related activities. The heat‐shock proteins Hsp70/Hsp110 protect cells against …
combat‐related activities. The heat‐shock proteins Hsp70/Hsp110 protect cells against …
Prenatal maternal factors in the development of cognitive impairments in the offspring
J Richetto, MA Riva - Journal of reproductive immunology, 2014 - Elsevier
Different environmental factors acting during sensitive prenatal periods can have a negative
impact on neurodevelopment and predispose the individual to the development of various …
impact on neurodevelopment and predispose the individual to the development of various …