Frontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders,
with around 30% of patients having a strong family history. The majority of that heritability is …

Neurodegenerative diseases are characterised by selective dysfunction and progressive
loss of synapses and neurons associated with pathologically altered proteins that deposit …

Frontotemporal dementia (FTD) is a heterogeneous clinical syndrome associated with
frontotemporal lobar degeneration (FTLD) as a relatively consistent neuropathological …

Frontotemporal dementia and amyotrophic lateral sclerosis are clinically and pathologically
overlapping disorders with shared genetic causes. We previously identified a disease locus …

Frontotemporal lobar degeneration (FTLD) represents a group of neurodegenerative brain
diseases with highly heterogeneous clinical, neuropathological and genetic characteristics …

Frontotemporal lobar degeneration with TPD-43-immunoreactive pathology (FTLD-TDP) is
subclassified based on the type and cortical laminar distribution of neuronal inclusions. The …

Introduction Frontotemporal dementia (FTD) is a complex neurodegenerative disorder,
characterized by a wide range of pathological conditions associated with the buildup of …

Frontotemporal lobar degeneration with TDP-43 immunoreactive (TDP-ir) inclusions (FTLD-
TDP) is sub-classified based on the pattern of neocortical pathology, with each subtype …

Although the right temporal variant frontotemporal dementia (rtvFTD) is characterised by
distinct clinical and radiological features, its underlying histopathology remains elusive …

Next-generation genetic sequencing (NGS) technologies facilitate the screening of multiple
genes linked to neurodegenerative dementia, but there are few reports about their use in …