Molecular pathogenesis and systemic therapies for hepatocellular carcinoma

JM Llovet, R Pinyol, RK Kelley, A El-Khoueiry… - Nature cancer, 2022 - nature.com
Hepatocellular carcinoma (HCC) remains one of the most prevalent and deadliest cancers.
The poor outcome associated with HCC is dramatically changing due to the advent of …

BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update

M Reig, A Forner, J Rimola, J Ferrer-Fàbrega… - Journal of …, 2022 - Elsevier
There have been major advances in the armamentarium for hepatocellular carcinoma
(HCC) since the last official update of the Barcelona Clinic Liver Cancer prognosis and …

Systemic treatment of hepatocellular carcinoma: An EASL position paper

J Bruix, SL Chan, PR Galle, L Rimassa, B Sangro - Journal of hepatology, 2021 - Elsevier
The last 5 years have witnessed relevant advances in the systemic treatment of
hepatocellular carcinoma. New data have emerged since the development of the EASL …

Systemic therapy for advanced hepatocellular carcinoma: ASCO guideline

JD Gordan, EB Kennedy, GK Abou-Alfa… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To develop an evidence-based clinical practice guideline to assist in clinical
decision making for patients with advanced hepatocellular carcinoma (HCC). METHODS …

[PDF][PDF] Preliminary evidence of safety and tolerability of atezolizumab plus bevacizumab in patients with hepatocellular carcinoma and Child‐Pugh A and B cirrhosis: a …

A D'Alessio, CAM Fulgenzi, N Nishida… - …, 2022 - Wiley Online Library
Abstract Background and Aims Atezolizumab plus bevacizumab (AtezoBev) is the standard
of care for first‐line treatment of unresectable HCC. No evidence exists as to its use in …

Targeted therapy for hepatocellular carcinoma

A Huang, XR Yang, WY Chung, AR Dennison… - Signal transduction and …, 2020 - nature.com
The last 3 years have seen the emergence of promising targeted therapies for the treatment
of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a …

[HTML][HTML] 2019 Chinese clinical guidelines for the management of hepatocellular carcinoma: updates and insights

DY Xie, ZG Ren, J Zhou, J Fan… - Hepatobiliary surgery and …, 2020 - ncbi.nlm.nih.gov
2019 Chinese clinical guidelines for the management of hepatocellular carcinoma: updates
and insights - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Recent advances in systemic therapy for hepatocellular carcinoma

H Zhang, W Zhang, L Jiang, Y Chen - Biomarker Research, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the most common and lethal malignant tumors in
the world. Therapeutic options for advanced HCC are limited. Systemic treatment, especially …

[HTML][HTML] Recent progress in treatment of hepatocellular carcinoma

Z Chen, H Xie, M Hu, T Huang, Y Hu… - American journal of …, 2020 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related death
worldwide. In the past decade, there have been improvements in non-drug therapies and …

Molecular therapies and precision medicine for hepatocellular carcinoma

JM Llovet, R Montal, D Sia, RS Finn - Nature reviews Clinical oncology, 2018 - nature.com
The global burden of hepatocellular carcinoma (HCC) is increasing and might soon surpass
an annual incidence of 1 million cases. Genomic studies have established the landscape of …