This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

Simple Summary The aim of this review is to provide a general overview about the
molecular markers (mutations and alterations) of thyroid cancers, present several molecular …

Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) have a
worse prognosis with respect to well differentiated TC, and the loss of the capability of up …

The thyroid hormone system is a main target of endocrine disruptor compounds (EDC) at all
levels of its intricately fine-tuned feedback regulation, synthesis, distribution, metabolism and …

Background The Italian Consensus for the Classification and Reporting of Thyroid Cytology
(ICCRTC) includes six diagnostic categories (TIR 1/1C, TIR 2, TIR 3A, TIR 3B, TIR 4, and TIR …

Thyroid cancer is the most common malignancy of the endocrine system. Fine-needle
aspiration (FNA) biopsy of thyroid nodules has become the gold standard procedure, in …

Papillary thyroid carcinomas (PTCs) are driven by a variety of molecular abnormalities
including BRAF, RAS, ALK, RET, and NTRK alterations. PTCs driven by the BRAFV600E …

Simple Summary This study aimed to investigate the relationship between the allele
frequency (AF) of the BRAF V600E mutation and the histopathological features of papillary …

Simple Summary PTEN mutation is an extremely rare mutation in thyroid nodules with no
clear prognostic indicators. In this multicenter study of 16 PTEN-mutated thyroid nodules, we …

Thyroid cancer is the predominant endocrine-related malignancy. ST6 β-galactoside α2, 6-
sialyltransferase 1 (ST6GAL1) has been studied in various types of cancers; however, the …