suPAR: a new biomarker for cardiovascular disease?

GW Hodges, CN Bang, K Wachtell… - Canadian Journal of …, 2015 - Elsevier
The fundamental role of inflammation in cardiovascular disease (CVD) has prompted
interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble …

[HTML][HTML] Soluble urokinase plasminogen activator receptor as a diagnostic and prognostic biomarker in cardiac disease

D Velissaris, N Zareifopoulos, I Koniari… - Journal of clinical …, 2021 - ncbi.nlm.nih.gov
This review summarizes the published literature referring to the use and validity of the
biomarker soluble urokinase plasminogen activator receptor (suPAR) when used for the …

High-sensitivity troponin T and N-terminal pro-B-type natriuretic peptide (NT-proBNP) and risk of incident heart failure in patients with CKD: the Chronic Renal …

N Bansal, AH Anderson, W Yang… - Journal of the …, 2015 - journals.lww.com
High-sensitivity troponin T (hsTnT) and N-terminal pro-B-type natriuretic peptide (NT-
proBNP) strongly predict heart failure (HF) in the general population. However, the …

Recent advances in understanding hypertension development in sub-Saharan Africa

AE Schutte, S Botha, CMT Fourie… - Journal of human …, 2017 - nature.com
Consistent reports indicate that hypertension is a particularly common finding in black
populations. Hypertension occurs at younger ages and is often more severe in terms of …

Analytical, biochemical and clearance considerations of soluble urokinase plasminogen activator receptor (suPAR) in healthy individuals

J Chew-Harris, S Appleby, AM Richards… - Clinical …, 2019 - Elsevier
Background Soluble urokinase plasminogen activator receptor (suPAR) is an emerging
marker of cardiovascular disease burden. Appropriate assessment of assay performance …

Soluble urokinase plasminogen activator receptor as a prognostic marker of all-cause and cardiovascular mortality in a black population

S Botha, CMT Fourie, R Schutte, J Eugen-Olsen… - International journal of …, 2015 - Elsevier
Background Elevated inflammatory markers such as C-reactive protein (CRP) and
interleukin-6 (IL-6) are well-known risk factors for cardiovascular mortality. The less familiar …

[HTML][HTML] Soluble urokinase plasminogen activator receptor (suPAR) levels predict damage accrual in patients with recent-onset systemic lupus erythematosus

H Enocsson, L Wirestam, C Dahle, L Padyukov… - Journal of …, 2020 - Elsevier
Objective The soluble urokinase plasminogen activator receptor (suPAR) has potential as a
prognosis and severity biomarker in several inflammatory and infectious diseases. In a …

[HTML][HTML] Unchanged plasma levels of the soluble urokinase plasminogen activator receptor in elective coronary artery bypass graft surgery patients and …

W Gozdzik, B Adamik, A Gozdzik, M Rachwalik… - PLoS …, 2014 - journals.plos.org
Objective and Design The soluble urokinase plasminogen activator receptor (suPAR) has
been recently recognized as a potential biological marker of various disease states, but the …

The association of oxidative stress with arterial compliance and vascular resistance in a bi-ethnic population: the SABPA study

MC Mokhaneli, CMT Fourie, S Botha… - Free radical …, 2016 - Taylor & Francis
A loss of arterial elasticity increases the risk for cardiovascular events. Oxidative injury to the
vessel wall may be one of the underlying mechanisms influencing arterial elasticity. We …

[HTML][HTML] An Overview of Vascular Dysfunction and Determinants: The Case of Children of African Ancestry

EN Matjuda, GA Engwa, CR Sewani-Rusike… - Frontiers in …, 2021 - frontiersin.org
The balance between dilatory and constrictive factors is important as it keeps blood vessels
in a homeostatic state. However, altered physiological processes as a result of obesity …