Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …

Precision medicine is becoming the standard of care in anti-cancer treatment. The
personalized precision management of cancer patients highly relies on the improvement of …

The apoptotic death of cardiomyocytes critically contributes to cardiac remodeling after
myocardial infarction (MI). Circular RNAs (circRNAs) are important regulators for a variety of …

Background The poor prognosis and rising incidence of esophageal adenocarcinoma
highlight the need for improved detection methods. The potential for circulating microRNAs …

Chemo-resistance, which is the main obstacle in cancer therapy, is caused by the onset of
drug-resistant cells in the heterogeneous cell population in cancer tissues. MicroRNAs …

How a cell determines a given phenotype upon damaged DNA is an open problem. Cell fate
decisions happen at cell cycle checkpoints and it is becoming clearer that the p53 pathway …

Abstract miR-424 (322)/-503 are mammal-specific members of the extended miR-15/107
microRNA family. They form a co-expression network with the imprinted lncRNA H19 in …

The inability of cancer cells in taking care of DNA damages can lead to cancer development
and/or progression. Due to the essential role of DNA repair in maintaining genomic stability …

It is believed that epigenetic modification plays roles in cancer initiation and progression.
Both microRNA and DNA methyltransferase are epigenetic regulation factors. It was found …

Lung cancer is the leading cause of cancer death worldwide due to its high incidence and
mortality. As the most common lung cancer, non-small cell lung cancer (NSCLC) is a terrible …