Alcohol use disorder (AUD) and chronic pain are enduring and devastating conditions that
share an intersecting epidemiology and neurobiology. Chronic alcohol use itself can …

Aims A close and bidirectional relationship between alcohol consumption and pain has
been previously reported and discussed in influential reviews. The goal of the present …

A complex relationship exists between the psychosocial environment and the perception
and experience of pain, and the mechanisms of the social communication of pain have yet to …

Alcohol consumption afflicts men and women differently. However, the underlying neuronal
mechanisms that contribute to the difference are mostly unexplored. Although more men …

Adolescent alcohol use can permanently alter brain function and lead to poor health
outcomes in adulthood. Emerging evidence suggests that alcohol use can predispose …

Alcohol use disorders (AUDs) and anxiety disorders (ADs) are often seen concurrently, but
their underlying cellular basis is unclear. For unclear reasons, the lateral habenula (LHb), a …

Hyperalgesia, which often occurs in people suffering from alcohol use disorder, may drive
excessive drinking and relapse. Emerging evidence suggests that the lateral habenula …

Opioids and alcohol are widely used to relieve pain, with their analgesic efficacy stemming
from rapid actions on both spinal and supraspinal nociceptive centers. As an extension of …

Background Alcohol binge drinking in humans is thought to increase the risk for alcohol use
disorder (AUD). Unclear is whether drinking patterns (eg, bingelike or stable drinking) …

Sex differences in chronic pain and alcohol abuse are not well understood. The
development of rodent models is imperative for investigating the underlying changes behind …