[HTML][HTML] The antimicrobial activity of innate host-directed therapies–a systematic review

T Shapira, M Christofferson, Y Av-Gay - International Journal of …, 2024 - Elsevier
Intracellular human pathogens are the deadliest infectious diseases and pose great difficulty
to effectively treat due to their protection inside the host cell and the development of …

[HTML][HTML] Something old, something new: ion Channel Blockers as potential anti-tuberculosis agents

SC Mitini-Nkhoma, ET Chimbayo, DT Mzinza… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis (TB) remains a challenging global health concern and claims more than a
million lives every year. We lack an effective vaccine and understanding of what constitutes …

Repurposing miconazole and tamoxifen for the treatment of Mycobacterium abscessus complex infections through in silico chemogenomics approach

LRB Anjos, VAF Costa, BJ Neves… - World Journal of …, 2023 - Springer
Drug repositioning is an alternative to overcome the complexity of the drug discovery and
approval procedures for the treatment of Mycobacterium abscessus Complex (MABSC) …

Ion Transport Modulators Differentially Modulate Inflammatory Responses in THP‐1‐Derived Macrophages

SC Mitini-Nkhoma, N Fernando… - Journal of …, 2021 - Wiley Online Library
Ion transport modulators are most commonly used to treat various noncommunicable
diseases including diabetes and hypertension. They are also known to bind to receptors on …

[PDF][PDF] 离子通道阻滞剂抗结核作用的研究进展

罗水清, 曾娅莉 - 中国医药导报 - yiyaodaobao.com.cn
结核病是由结核分枝杆菌(MTB) 感染引起的全球性公共疾病, 结核病的治疗需要长期使用多种
药物, 并因依从性和耐药性问题变得复杂且漫长, MTB 对药物的敏感性T 定程度上是由细菌和 …

Something Old, Something New: Ion Channel Blockers as Potential Anti-Tuberculosis Agents

B Mishra, M Saqib, K Kota… - Repurposed Drugs as …, 2022 - books.google.com
Tuberculosis (TB) is an airborne infection contracted by inhalation of droplet nuclei
containing viable Mycobacterium tuberculosis (Mtb) that are released into the air by a …