An expanded molecular and systems toolbox for imaging, mapping, and controlling local translation

W Onchan, C Attakitbancha, C Uttamapinant - Current Opinion in Chemical …, 2024 - Elsevier
Localized protein translation occurs through trafficking of mRNAs and protein translation
machineries to different compartments of the cell, leading to rapid on-site synthesis of …

Dysregulation of the mTOR-FMRP pathway and synaptic plasticity in an environmental model of ASD

ML Hilal, E Rosina, G Pedini, L Restivo, C Bagni - Molecular Psychiatry, 2024 - nature.com
Abstract Autism Spectrum Disorder (ASD) is caused by genetic, epigenetic, and
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …

Neurodevelopmental Genetic Associations Across the Translational Space-Time Continuum

MA Gachechiladze… - Biological …, 2024 - biologicalpsychiatryjournal.com
Genes encoding machinery for synaptic development and plasticity have been shown to
play a role in the pathophysiology of neurodevelopmental psychiatric disorders such as …

[PDF][PDF] Translational study on the role of genetic and prenatal risk factors in neurodevelopmental psychiatric disorders

A Yotova - 2024 - d-nb.info
Neurodevelopmental psychiatric disorders (NPDs), such as attention deficit hyperactivity
disorder (ADHD), autism spectrum disorder (ASD), and schizophrenia (SCZ), and their …