The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

The widespread applications of benzophenone (BP) photochemistry in biological chemistry,
bioorganic chemistry, and material science have been prominent in both academic and …

Chemical tools and methods that report on G protein-coupled receptor (GPCR) expression
levels and receptor occupancy by small molecules are highly desirable. We report the …

Cannabinoid receptor 2 (CB2) is a promising target for the treatment of neuroinflammation
and other diseases. However, a lack of understanding of its complex signaling in cells and …

A novel synthetic route for making (−)-CBD and its derivatives bearing various C4′-side
chains is developed by a late-stage diversification method. Starting from commercially …

Lipids modulate the function of many ion channels, possibly through direct lipid-protein
interactions. The recent outpouring of ion channel structures by cryo-EM has revealed many …

The synthesis and characterization of four fully-conjugated indacenedithiophenes (IDTs) are
disclosed. In contrast to anthradithiophenes, regioselective synthesis of both syn and anti …

An efficient aminocatalytic enantioselective double-activation strategy has been developed
that combines several different aminocatalytic modes in a cascade process, such as iminium …

My involvement with the field of cannabinoids spans close to 3 decades and covers a major
part of my scientific career. It also reflects the robust progress in this initially largely …

An organocatalytic asymmetric [3+ 2] cycloaddition of oxindole-based azomethine ylides
with 3-nitro-2H-chromenes has been developed. This reaction provides a facile approach to …