For more than 50 years, psychologists, gerontologists, and, more recently, neuroscientists
have considered the possibility of successful aging. How to define successful aging remains …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Physical exercise, particularly aerobic exercise, is documented as providing a low cost
regimen to counter well-documented cognitive declines including memory, executive …

The concept of brain maintenance refers to the preservation of brain integrity in older age,
while cognitive reserve refers to the capacity to maintain cognition in the presence of …

Decline in cognitive skills, especially in memory, is often viewed as part of “normal” aging.
Yet some individuals “age better” than others. Building on prior research showing that …

Although meditation is believed to be over five thousand years old, scientific research on it is
in its infancy. Mitigating the extensive negative biochemical effects of stress is a superficially …

Research into cognitive resilience imaging markers may help determine the clinical
significance of Alzheimer's disease pathology among older adults over 80 years (80+). In …

Abstract The Northwestern University SuperAging Project recruits community dwellers over
the age of 80 who have unusually high performance on tests of episodic memory. In a …

Background The concept of reserve was established to account for the observation that a
given degree of neurodegenerative pathology may result in varying degrees of symptoms in …

This human study is based on an established cohort of “SuperAgers,” 80+-year-old
individuals with episodic memory function at a level equal to, or better than, individuals 20 …