Micro and nano-scale technologies for cell mechanics

M Unal, Y Alapan, H Jia, AG Varga, K Angelino… - …, 2014 - hrcak.srce.hr
Sažetak Cell mechanics is a multidisciplinary field that bridges cell biology with fundamental
mechanics, and micro and nanotechnology, which synergize to help us better understand …

Investigation into local cell mechanics by atomic force microscopy mapping and optical tweezer vertical indentation

G Coceano, MS Yousafzai, W Ma, F Ndoye… - …, 2015 - iopscience.iop.org
Investigating the mechanical properties of cells could reveal a potential source of label-free
markers of cancer progression, based on measurable viscoelastic parameters. The Young's …

Substrate-dependent cell elasticity measured by optical tweezers indentation

MS Yousafzai, F Ndoye, G Coceano, J Niemela… - Optics and Lasers in …, 2016 - Elsevier
In the last decade, cell elasticity has been widely investigated as a potential label free
indicator for cellular alteration in different diseases, cancer included. Cell elasticity can be …

Compromised Biomechanical Properties, Cell–Cell Adhesion and Nanotubes Communication in Cardiac Fibroblasts Carrying the Lamin A/C D192G Mutation

V Lachaize, B Peña, C Ciubotaru, D Cojoc… - International Journal of …, 2021 - mdpi.com
Clinical effects induced by arrhythmogenic cardiomyopathy (ACM) originate from a large
spectrum of genetic variations, including the missense mutation of the lamin A/C gene …

Substrate stiffness mediates formation of novel cytoskeletal structures in fibroblasts during cell–microspheres interaction

O Adamczyk, Z Baster, M Szczypior… - International Journal of …, 2021 - mdpi.com
It is well known that living cells interact mechanically with their microenvironment. Many
basic cell functions, like migration, proliferation, gene expression, and differentiation, are …

The influence of lateral forces on the cell stiffness measurement by optical tweezers vertical indentation

F Ndoye, MS Yousafzai, G Coceano… - International Journal …, 2016 - Taylor & Francis
We studied the lateral forces arising during the vertical indentation of the cell membrane by
an optically trapped microbead, using back focal plane interferometry to determine force …

Cytoskeleton modification and cholesterol depletion affect membrane properties and caveolae positioning of CHO cells

M Grundner, Š Zemljič Jokhadar - The Journal of Membrane Biology, 2014 - Springer
The formation of protrusions is necessary for numerous biological processes. It involves
extension of the plasma membrane, and the force needed for this is provided by the actin …

Experimental determination of trapping efficiency of optical tweezers

H Cabrera, JJ Suárez-Vargas, A López… - Philosophical …, 2013 - Taylor & Francis
We report an experimental determination of trapping efficiency of optical fields acting on
spherical particles diluted in viscous fluids. This parameter was derived from experimentally …

The mathematical cell model reconstructed from interference microscopy data

AA Rogotnev, AS Nikitiuk, OB Naimark… - AIP Conference …, 2017 - pubs.aip.org
The mathematical model of cell dynamics is developed to link the dynamics of the phase cell
thickness with the signs of the oncological pathology. The measurements of irregular …

Cancer cell mechanics and cell microenvironment: an optical tweezers study

MS Yousafzai - 2016 - arts.units.it
Since cancer metastasis is a complex process, lot of research has been carried out to
identify different hallmarks for its diagnosis and cure. Mechanical alterations in cancer cells …