The treatment of type 1 diabetes mellitus consists of external replacement of the functions of
β cells in an attempt to achieve blood levels of glucose as close to the normal range as …

Insulin detemir (Levemir®) is a long-acting insulin analogue indicated for use as basal
insulin therapy in patients with type 1 or 2 diabetes mellitus. The protracted action of insulin …

This is the author's manuscript of the article published in final edited form as: Sundberg, F.,
Barnard, K., Cato, A., Beaufort, C. de, DiMeglio, LA, Dooley, G.,… Hanas, R.(2017) …

Background People with type 1 diabetes mellitus (T1DM) need treatment with insulin for
survival. Whether any particular type of (ultra‐) long‐acting insulin provides benefit …

Background Avoidance of hypoglycemia is a key consideration in treating young children
with type 1 diabetes (T1DM). Key Objective To evaluate hypoglycemia with insulin glargine …

Abstract Aims This 52‐week, randomized, multinational, open‐label, parallel‐group, non‐
inferiority trial investigated the efficacy and safety of basal–bolus treatment with insulin …

Optimizing glycemic control without risking hypoglycemia is crucial in toddlers and
preschoolers with type 1 diabetes (T1D) to avoid cognitive impairment later in life. Hence …

La tecnología recombinante del ADN ha permitido disponer de análogos de insulina
humana para el tratamiento de la diabetes mellitus, cuya eficacia y seguridad han permitido …

The Impact of Technology on Current Diabetes Management - Pediatric Clinics Skip to Main
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Since insulin is the unique and life-long therapy in type 1 diabetes and classical insulin
preparations have certain limitations due to their pharmacokinetic and pharmacodynamic …