Dendrimers in drug research
U Boas, PMH Heegaard - Chemical Society Reviews, 2004 - pubs.rsc.org
Dendrimers are versatile, derivatisable, well-defined, compartmentalised chemical polymers
with sizes and physicochemical properties resembling those of biomolecules eg proteins …
with sizes and physicochemical properties resembling those of biomolecules eg proteins …
Strategies for targeting protein–protein interactions with synthetic agents
H Yin, AD Hamilton - Angewandte Chemie International Edition, 2005 - Wiley Online Library
The development of small‐molecule modulators of protein–protein interactions is a
formidable goal, albeit one that possesses significant potential for the discovery of novel …
formidable goal, albeit one that possesses significant potential for the discovery of novel …
Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells
L Yi, Z Li, K Yuan, X Qu, J Chen, G Wang… - Journal of …, 2004 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS,
which caused a global panic in 2003. We describe here the screening of Chinese herbal …
which caused a global panic in 2003. We describe here the screening of Chinese herbal …
Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms
Severe acute respiratory syndrome (SARS) is an infectious and highly contagious disease
that is caused by SARS coronavirus (SARS-CoV) and for which there are currently no …
that is caused by SARS coronavirus (SARS-CoV) and for which there are currently no …
Withanone from Withania somnifera may inhibit novel coronavirus (COVID-19) entry by disrupting interactions between viral S-protein receptor binding domain and …
Background Newly emerged COVID-19 has been shown to engage the host cell ACE2
through its spike protein receptor binding domain (RBD). Here we show that natural …
through its spike protein receptor binding domain (RBD). Here we show that natural …
[PDF][PDF] Pharmaceutical applications of dendrimers: promising nanocarriers for drug delivery
Y Cheng, J Wang, T Rao, X He, T Xu - Front Biosci, 2008 - article.imrpress.com
Introduction 3. Delivery of non-steroidal anti-inflammatory drugs by dendrimers 3.1. Non-
covalent complexation of NSAIDs 3.2. Covalent conjugation of NSAIDs 4. Delivery of anti …
covalent complexation of NSAIDs 3.2. Covalent conjugation of NSAIDs 4. Delivery of anti …
[图书][B] Synthetic multivalent molecules: concepts and biomedical applications
S Choi - 2004 - books.google.com
This book provides basic principles of multivalent interactions found in biological systems as
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …
Respiratory syncytial virus-neutralizing monoclonal antibodies motavizumab and palivizumab inhibit fusion
K Huang, L Incognito, X Cheng, ND Ulbrandt… - Journal of …, 2010 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is a major cause of virus-induced respiratory disease and
hospitalization in infants. Palivizumab, an RSV-neutralizing monoclonal antibody, is used …
hospitalization in infants. Palivizumab, an RSV-neutralizing monoclonal antibody, is used …
Antiviral drugs specific for coronaviruses in preclinical development
AO Adedeji, SG Sarafianos - Current opinion in virology, 2014 - Elsevier
Highlights•Coronaviruses are RNA viruses that cause systemic diseases in humans and
animals.•There are no approved drugs for the treatment of coronavirus infections.•Several …
animals.•There are no approved drugs for the treatment of coronavirus infections.•Several …
[图书][B] Polymers in drug delivery
IF Uchegbu, AG Schatzlein - 2006 - books.google.com
In recent years there has been an explosion in the use of polymers to solve various
biomedical problems. Polymers play a crucial role in controlling drug release rate …
biomedical problems. Polymers play a crucial role in controlling drug release rate …