[HTML][HTML] Anticancer activities of TCM and their active components against tumor metastasis

K Wang, Q Chen, Y Shao, S Yin, C Liu, Y Liu… - Biomedicine & …, 2021 - Elsevier
Abstract Traditional Chinese Medicine (TCM) has the characteristics of multiple targets,
slight side effects and good therapeutic effects. Good anti-tumor effects are shown by …

Tumor-associated macrophages: role in cancer development and therapeutic implications

A Salmaninejad, SF Valilou, A Soltani, S Ahmadi… - Cellular oncology, 2019 - Springer
Abstract Background Tumor-associated macrophages (TAMs) are known to play important
roles in the initiation and progression of human cancers, as well as in angiogenesis. TAMs …

Current insights into the metastasis of epithelial ovarian cancer-hopes and hurdles

M Yousefi, S Dehghani, R Nosrati, M Ghanei… - Cellular Oncology, 2020 - Springer
Background Ovarian cancer is the most lethal gynecologic cancer and the fifth leading
cause of cancer-related mortality in women worldwide. Despite various attempts to improve …

Organ-specific metastasis of breast cancer: molecular and cellular mechanisms underlying lung metastasis

M Yousefi, R Nosrati, A Salmaninejad, S Dehghani… - Cellular Oncology, 2018 - Springer
Background Breast cancer (BC) is the most common type of cancer in women and the
second cause of cancer-related mortality world-wide. The majority of BC-related deaths is …

Improving CNS delivery to brain metastases by blood–tumor barrier disruption

SA Sprowls, TA Arsiwala, JR Bumgarner, N Shah… - Trends in cancer, 2019 - cell.com
Brain metastases encompass nearly 80% of all intracranial tumors. A late stage diagnosis
confers a poor prognosis, with patients typically surviving less than 2 years. Poor survival …

[HTML][HTML] The long-term and short-term efficacy of immunotherapy in non-small cell lung cancer patients with brain metastases: a systematic review and meta-analysis

X Chu, L Niu, G Xiao, H Peng, F Deng, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Background Although immunotherapy has been widely used, there is currently no research
comparing immunotherapy for non-small cell lung cancer (NSCLC) patients with brain …

Curcumin: A potent agent to reverse epithelial-to-mesenchymal transition

A Bahrami, M Majeed, A Sahebkar - Cellular Oncology, 2019 - Springer
Background Epithelial-to-mesenchymal transition (EMT) is involved in tumor progression,
invasion, migration and metastasis. EMT is a process by which polarized epithelial cells …

Brain microvascular endothelial cell exosome–mediated S100A16 up‐regulation confers small‐cell lung cancer cell survival in brain

ZH Xu, ZW Miao, QZ Jiang, DX Gan, XG Wei… - The FASEB …, 2019 - Wiley Online Library
Small cell lung cancer (SCLC) is the most aggressive histologic subtype of lung cancer, with
a strong predilection for early brain metastases. Despite efforts and advances in new …

[HTML][HTML] CircRNA_100395 inhibits cell proliferation and metastasis in ovarian cancer via regulating miR-1228/p53/epithelial-mesenchymal transition (EMT) axis

X Li, S Lin, Z Mo, J Jiang, H Tang, C Wu… - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Purpose: Circular RNAs (circRNAs) have been reported to regulate the incidence of tumor
by regulating the transcriptional level and post-transcriptional level of tumor-related genes …

[HTML][HTML] Mutational profiles of primary pulmonary adenocarcinoma and paired brain metastases disclose the importance of KRAS mutations

E Vassella, E Kashani, P Zens, A Kündig… - European Journal of …, 2021 - Elsevier
Background Brain metastases present a significant complication in lung cancer with an
unmet therapeutic need. Methods In this single-centre, retrospective study, we genotyped a …